Gómez-Galeno JE - Search Results

1

A Potent and Selective AMPK Activator That Inhibits de Novo Lipogenesis.

Gómez-Galeno JE, Dang Q, Nguyen TH, Boyer SH, Grote MP, Sun Z, Chen M, Craigo WA, van Poelje PD, MacKenna DA, Cable EE, Rolzin PA, Finn PD, Chi B, Linemeyer DL, Hecker SJ, Erion MD. Gómez-Galeno JE, et al. ACS Med Chem Lett. 2010 Aug 30;1(9):478-82. doi: 10.1021/ml100143q. eCollection 2010 Dec 9. ACS Med Chem Lett. 2010. PMID: 24900234 Free PMC article.

2

Adenosine kinase inhibitors. 5. Synthesis, enzyme inhibition, and analgesic activity of diaryl-erythro-furanosyltubercidin analogues.

Boyer SH, Ugarkar BG, Solbach J, Kopcho J, Matelich MC, Ollis K, Gomez-Galeno JE, Mendonca R, Tsuchiya M, Nagahisa A, Nakane M, Wiesner JB, Erion MD. Boyer SH, et al. Among authors: gomez galeno je. J Med Chem. 2005 Oct 6;48(20):6430-41. doi: 10.1021/jm0503650. J Med Chem. 2005. PMID: 16190769

3

Synthesis and characterization of a novel liver-targeted prodrug of cytosine-1-beta-D-arabinofuranoside monophosphate for the treatment of hepatocellular carcinoma.

Boyer SH, Sun Z, Jiang H, Esterbrook J, Gómez-Galeno JE, Craigo W, Reddy KR, Ugarkar BG, MacKenna DA, Erion MD. Boyer SH, et al. Among authors: gomez galeno je. J Med Chem. 2006 Dec 28;49(26):7711-20. doi: 10.1021/jm0607449. J Med Chem. 2006. PMID: 17181153

4

Pradefovir: a prodrug that targets adefovir to the liver for the treatment of hepatitis B.

Reddy KR, Matelich MC, Ugarkar BG, Gómez-Galeno JE, DaRe J, Ollis K, Sun Z, Craigo W, Colby TJ, Fujitaki JM, Boyer SH, van Poelje PD, Erion MD. Reddy KR, et al. Among authors: gomez galeno je. J Med Chem. 2008 Feb 14;51(3):666-76. doi: 10.1021/jm7012216. Epub 2008 Jan 4. J Med Chem. 2008. PMID: 18173234

5

Design, synthesis, and characterization of a series of cytochrome P(450) 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver.

Erion MD, Reddy KR, Boyer SH, Matelich MC, Gomez-Galeno J, Lemus RH, Ugarkar BG, Colby TJ, Schanzer J, Van Poelje PD. Erion MD, et al. J Am Chem Soc. 2004 Apr 28;126(16):5154-63. doi: 10.1021/ja031818y. J Am Chem Soc. 2004. PMID: 15099098

6

An efficient synthesis of pyrrolo[2,3-d]pyrimidines via inverse electron demand diels-alder reactions of 2-amino-4-cyanopyrroles with 1,3,5-triazines.

Dang Q, Gomez-Galeno JE. Dang Q, et al. Among authors: gomez galeno je. J Org Chem. 2002 Nov 29;67(24):8703-5. doi: 10.1021/jo026309d. J Org Chem. 2002. PMID: 12444666

7

Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes.

Cashman JR, Ryan D, McKeithan WL, Okolotowicz K, Gomez-Galeno J, Johnson M, Sampson KJ, Kass RS, Pezhouman A, Karagueuzian HS, Mercola M. Cashman JR, et al. J Med Chem. 2021 May 13;64(9):5384-5403. doi: 10.1021/acs.jmedchem.0c01545. Epub 2021 May 4. J Med Chem. 2021. PMID: 33942619

8

b-Annulated 1,4-dihydropyridines as Notch inhibitors.

Gómez-Galeno JE, Hurtado C, Cheng J, Yardimci C, Mercola M, Cashman JR. Gómez-Galeno JE, et al. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3363-3367. doi: 10.1016/j.bmcl.2018.09.002. Epub 2018 Sep 5. Bioorg Med Chem Lett. 2018. PMID: 30201292 Free PMC article.

9

Human iPSC-derived cardiomyocytes and pyridyl-phenyl mexiletine analogs.

Johnson M, Gomez-Galeno J, Ryan D, Okolotowicz K, McKeithan WL, Sampson KJ, Kass RS, Mercola M, Cashman JR. Johnson M, et al. Bioorg Med Chem Lett. 2021 Aug 15;46:128162. doi: 10.1016/j.bmcl.2021.128162. Epub 2021 May 29. Bioorg Med Chem Lett. 2021. PMID: 34062251

10

Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity.

McKeithan WL, Feyen DAM, Bruyneel AAN, Okolotowicz KJ, Ryan DA, Sampson KJ, Potet F, Savchenko A, Gómez-Galeno J, Vu M, Serrano R, George AL Jr, Kass RS, Cashman JR, Mercola M. McKeithan WL, et al. Cell Stem Cell. 2020 Nov 5;27(5):813-821.e6. doi: 10.1016/j.stem.2020.08.003. Epub 2020 Sep 14. Cell Stem Cell. 2020. PMID: 32931730 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

13 results

Search Page