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Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment.
Naipal KA, Verkaik NS, Ameziane N, van Deurzen CH, Ter Brugge P, Meijers M, Sieuwerts AM, Martens JW, O'Connor MJ, Vrieling H, Hoeijmakers JH, Jonkers J, Kanaar R, de Winter JP, Vreeswijk MP, Jager A, van Gent DC. Naipal KA, et al. Among authors: van deurzen ch, van gent dc. Clin Cancer Res. 2014 Sep 15;20(18):4816-26. doi: 10.1158/1078-0432.CCR-14-0571. Epub 2014 Jun 24. Clin Cancer Res. 2014. PMID: 24963051
Molecular mechanisms of DNA double strand break repair.
Kanaar R, Hoeijmakers JH, van Gent DC. Kanaar R, et al. Among authors: van gent dc. Trends Cell Biol. 1998 Dec;8(12):483-9. doi: 10.1016/s0962-8924(98)01383-x. Trends Cell Biol. 1998. PMID: 9861670 Review.
Human Rad50/Mre11 is a flexible complex that can tether DNA ends.
de Jager M, van Noort J, van Gent DC, Dekker C, Kanaar R, Wyman C. de Jager M, et al. Among authors: van gent dc, van noort j. Mol Cell. 2001 Nov;8(5):1129-35. doi: 10.1016/s1097-2765(01)00381-1. Mol Cell. 2001. PMID: 11741547 Free article.
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.
Noordzij JG, Verkaik NS, van der Burg M, van Veelen LR, de Bruin-Versteeg S, Wiegant W, Vossen JM, Weemaes CM, de Groot R, Zdzienicka MZ, van Gent DC, van Dongen JJ. Noordzij JG, et al. Among authors: van dongen jj, van gent dc, van veelen lr, van der burg m. Blood. 2003 Feb 15;101(4):1446-52. doi: 10.1182/blood-2002-01-0187. Epub 2002 Oct 24. Blood. 2003. PMID: 12406895 Free article.
112 results