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Cowpox virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP.
J Immunol. 2014 Aug 15;193(4):1578-89. doi: 10.4049/jimmunol.1400964. Epub 2014 Jul 14.
J Immunol. 2014.
PMID: 25024387
Free PMC article.
The influence of TAP1 and TAP2 gene polymorphisms on TAP function and its inhibition by viral immune evasion proteins.
Praest P, Luteijn RD, Brak-Boer IGJ, Lanfermeijer J, Hoelen H, Ijgosse L, Costa AI, Gorham RD Jr, Lebbink RJ, Wiertz EJHJ.
Praest P, et al. Among authors: hoelen h.
Mol Immunol. 2018 Sep;101:55-64. doi: 10.1016/j.molimm.2018.05.025. Epub 2018 Jun 4.
Mol Immunol. 2018.
PMID: 29879547
Free article.
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A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation.
van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, Lebbink RJ.
van de Weijer ML, et al. Among authors: hoelen h.
Nat Commun. 2014 May 8;5:3832. doi: 10.1038/ncomms4832.
Nat Commun. 2014.
PMID: 24807418
Free PMC article.
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Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.
Hoelen H, Zaldumbide A, van Leeuwen WF, Torfs EC, Engelse MA, Hassan C, Lebbink RJ, de Koning EJ, Resssing ME, de Ru AH, van Veelen PA, Hoeben RC, Roep BO, Wiertz EJ.
Hoelen H, et al.
PLoS One. 2015 Jun 24;10(6):e0128206. doi: 10.1371/journal.pone.0128206. eCollection 2015.
PLoS One. 2015.
PMID: 26107514
Free PMC article.
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The primary folding defect and rescue of ΔF508 CFTR emerge during translation of the mutant domain.
Hoelen H, Kleizen B, Schmidt A, Richardson J, Charitou P, Thomas PJ, Braakman I.
Hoelen H, et al.
PLoS One. 2010 Nov 30;5(11):e15458. doi: 10.1371/journal.pone.0015458.
PLoS One. 2010.
PMID: 21152102
Free PMC article.
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Proinsulin degradation and presentation of a proinsulin B-chain autoantigen involves ER-associated protein degradation (ERAD)-enzyme UBE2G2.
Cremer T, Hoelen H, van de Weijer ML, Janssen GM, Costa AI, van Veelen PA, Lebbink RJ, Wiertz EJHJ.
Cremer T, et al. Among authors: hoelen h.
PLoS One. 2024 May 24;19(5):e0287877. doi: 10.1371/journal.pone.0287877. eCollection 2024.
PLoS One. 2024.
PMID: 38787820
Free PMC article.
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The Folding Pathway of ABC Transporter CFTR: Effective and Robust.
van der Sluijs P, Hoelen H, Schmidt A, Braakman I.
van der Sluijs P, et al. Among authors: hoelen h.
J Mol Biol. 2024 Apr 26:168591. doi: 10.1016/j.jmb.2024.168591. Online ahead of print.
J Mol Biol. 2024.
PMID: 38677493
Free article.
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