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Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.
Walz S, Lorenzin F, Morton J, Wiese KE, von Eyss B, Herold S, Rycak L, Dumay-Odelot H, Karim S, Bartkuhn M, Roels F, Wüstefeld T, Fischer M, Teichmann M, Zender L, Wei CL, Sansom O, Wolf E, Eilers M. Walz S, et al. Among authors: zender l. Nature. 2014 Jul 24;511(7510):483-7. doi: 10.1038/nature13473. Epub 2014 Jul 9. Nature. 2014. PMID: 25043018 Free PMC article.
Deregulated MYC expression induces dependence upon AMPK-related kinase 5.
Liu L, Ulbrich J, Müller J, Wüstefeld T, Aeberhard L, Kress TR, Muthalagu N, Rycak L, Rudalska R, Moll R, Kempa S, Zender L, Eilers M, Murphy DJ. Liu L, et al. Among authors: zender l. Nature. 2012 Mar 28;483(7391):608-12. doi: 10.1038/nature10927. Nature. 2012. PMID: 22460906
MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma.
Krenz B, Gebhardt-Wolf A, Ade CP, Gaballa A, Roehrig F, Vendelova E, Baluapuri A, Eilers U, Gallant P, D'Artista L, Wiegering A, Gasteiger G, Rosenfeldt MT, Bauer S, Zender L, Wolf E, Eilers M. Krenz B, et al. Among authors: zender l. Cancer Res. 2021 Aug 15;81(16):4242-4256. doi: 10.1158/0008-5472.CAN-21-1677. Epub 2021 Jun 18. Cancer Res. 2021. PMID: 34145038 Free PMC article.
A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
Acosta JC, Banito A, Wuestefeld T, Georgilis A, Janich P, Morton JP, Athineos D, Kang TW, Lasitschka F, Andrulis M, Pascual G, Morris KJ, Khan S, Jin H, Dharmalingam G, Snijders AP, Carroll T, Capper D, Pritchard C, Inman GJ, Longerich T, Sansom OJ, Benitah SA, Zender L, Gil J. Acosta JC, et al. Among authors: zender l. Nat Cell Biol. 2013 Aug;15(8):978-90. doi: 10.1038/ncb2784. Epub 2013 Jun 16. Nat Cell Biol. 2013. PMID: 23770676 Free PMC article.
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.
Rudalska R, Dauch D, Longerich T, McJunkin K, Wuestefeld T, Kang TW, Hohmeyer A, Pesic M, Leibold J, von Thun A, Schirmacher P, Zuber J, Weiss KH, Powers S, Malek NP, Eilers M, Sipos B, Lowe SW, Geffers R, Laufer S, Zender L. Rudalska R, et al. Among authors: zender l. Nat Med. 2014 Oct;20(10):1138-46. doi: 10.1038/nm.3679. Epub 2014 Sep 14. Nat Med. 2014. PMID: 25216638 Free PMC article.
Necroptosis microenvironment directs lineage commitment in liver cancer.
Seehawer M, Heinzmann F, D'Artista L, Harbig J, Roux PF, Hoenicke L, Dang H, Klotz S, Robinson L, Doré G, Rozenblum N, Kang TW, Chawla R, Buch T, Vucur M, Roth M, Zuber J, Luedde T, Sipos B, Longerich T, Heikenwälder M, Wang XW, Bischof O, Zender L. Seehawer M, et al. Among authors: zender l. Nature. 2018 Oct;562(7725):69-75. doi: 10.1038/s41586-018-0519-y. Epub 2018 Sep 12. Nature. 2018. PMID: 30209397 Free PMC article.
184 results