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Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo.
Rudicell RS, Kwon YD, Ko SY, Pegu A, Louder MK, Georgiev IS, Wu X, Zhu J, Boyington JC, Chen X, Shi W, Yang ZY, Doria-Rose NA, McKee K, O'Dell S, Schmidt SD, Chuang GY, Druz A, Soto C, Yang Y, Zhang B, Zhou T, Todd JP, Lloyd KE, Eudailey J, Roberts KE, Donald BR, Bailer RT, Ledgerwood J; NISC Comparative Sequencing Program; Mullikin JC, Shapiro L, Koup RA, Graham BS, Nason MC, Connors M, Haynes BF, Rao SS, Roederer M, Kwong PD, Mascola JR, Nabel GJ. Rudicell RS, et al. Among authors: connors m. J Virol. 2014 Nov;88(21):12669-82. doi: 10.1128/JVI.02213-14. Epub 2014 Aug 20. J Virol. 2014. PMID: 25142607 Free PMC article.
Resistance to respiratory syncytial virus (RSV) challenge induced by infection with a vaccinia virus recombinant expressing the RSV M2 protein (Vac-M2) is mediated by CD8+ T cells, while that induced by Vac-F or Vac-G recombinants is mediated by antibodies.
Connors M, Kulkarni AB, Collins PL, Firestone CY, Holmes KL, Morse HC 3rd, Murphy BR. Connors M, et al. J Virol. 1992 Feb;66(2):1277-81. doi: 10.1128/JVI.66.2.1277-1281.1992. J Virol. 1992. PMID: 1731105 Free PMC article.
HIV preferentially infects HIV-specific CD4+ T cells.
Douek DC, Brenchley JM, Betts MR, Ambrozak DR, Hill BJ, Okamoto Y, Casazza JP, Kuruppu J, Kunstman K, Wolinsky S, Grossman Z, Dybul M, Oxenius A, Price DA, Connors M, Koup RA. Douek DC, et al. Among authors: connors m. Nature. 2002 May 2;417(6884):95-8. doi: 10.1038/417095a. Nature. 2002. PMID: 11986671
The differential ability of HLA B*5701+ long-term nonprogressors and progressors to restrict human immunodeficiency virus replication is not caused by loss of recognition of autologous viral gag sequences.
Migueles SA, Laborico AC, Imamichi H, Shupert WL, Royce C, McLaughlin M, Ehler L, Metcalf J, Liu S, Hallahan CW, Connors M. Migueles SA, et al. Among authors: connors m. J Virol. 2003 Jun;77(12):6889-98. doi: 10.1128/jvi.77.12.6889-6898.2003. J Virol. 2003. PMID: 12768008 Free PMC article.
433 results