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Typing Pseudomonas aeruginosa Isolates with Ultrahigh Resolution MALDI-FTICR Mass Spectrometry.
Fleurbaaij F, Kraakman ME, Claas EC, Knetsch CW, van Leeuwen HC, van der Burgt YE, Veldkamp KE, Vos MC, Goessens W, Mertens BJ, Kuijper EJ, Hensbergen PJ, Nicolardi S. Fleurbaaij F, et al. Among authors: van leeuwen hc, van der burgt ye. Anal Chem. 2016 Jun 7;88(11):5996-6003. doi: 10.1021/acs.analchem.6b01037. Epub 2016 May 10. Anal Chem. 2016. PMID: 27123572
A novel secreted metalloprotease (CD2830) from Clostridium difficile cleaves specific proline sequences in LPXTG cell surface proteins.
Hensbergen PJ, Klychnikov OI, Bakker D, van Winden VJ, Ras N, Kemp AC, Cordfunke RA, Dragan I, Deelder AM, Kuijper EJ, Corver J, Drijfhout JW, van Leeuwen HC. Hensbergen PJ, et al. Among authors: van winden vj, van leeuwen hc. Mol Cell Proteomics. 2014 May;13(5):1231-44. doi: 10.1074/mcp.M113.034728. Epub 2014 Mar 12. Mol Cell Proteomics. 2014. PMID: 24623589 Free PMC article.
Clostridium difficile secreted Pro-Pro endopeptidase PPEP-1 (ZMP1/CD2830) modulates adhesion through cleavage of the collagen binding protein CD2831.
Hensbergen PJ, Klychnikov OI, Bakker D, Dragan I, Kelly ML, Minton NP, Corver J, Kuijper EJ, Drijfhout JW, van Leeuwen HC. Hensbergen PJ, et al. Among authors: van leeuwen hc. FEBS Lett. 2015 Dec 21;589(24 Pt B):3952-8. doi: 10.1016/j.febslet.2015.10.027. Epub 2015 Oct 29. FEBS Lett. 2015. PMID: 26522134 Free article.
A Novel Fic (Filamentation Induced by cAMP) Protein from Clostridium difficile Reveals an Inhibitory Motif-independent Adenylylation/AMPylation Mechanism.
Dedic E, Alsarraf H, Welner DH, Østergaard O, Klychnikov OI, Hensbergen PJ, Corver J, van Leeuwen HC, Jørgensen R. Dedic E, et al. Among authors: van leeuwen hc. J Biol Chem. 2016 Jun 17;291(25):13286-300. doi: 10.1074/jbc.M115.705491. Epub 2016 Apr 13. J Biol Chem. 2016. PMID: 27076635 Free PMC article.
Discovery of a new Pro-Pro endopeptidase, PPEP-2, provides mechanistic insights into the differences in substrate specificity within the PPEP family.
Klychnikov OI, Shamorkina TM, Weeks SD, van Leeuwen HC, Corver J, Drijfhout JW, van Veelen PA, Sluchanko NN, Strelkov SV, Hensbergen PJ. Klychnikov OI, et al. Among authors: van leeuwen hc. J Biol Chem. 2018 Jul 13;293(28):11154-11165. doi: 10.1074/jbc.RA118.003244. Epub 2018 May 23. J Biol Chem. 2018. PMID: 29794027 Free PMC article.
Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans.
Fleurbaaij F, Henneman AA, Corver J, Knetsch CW, Smits WK, Nauta ST, Giera M, Dragan I, Kumar N, Lawley TD, Verhoeven A, van Leeuwen HC, Kuijper EJ, Hensbergen PJ. Fleurbaaij F, et al. Among authors: van leeuwen hc. Sci Rep. 2018 May 25;8(1):8181. doi: 10.1038/s41598-018-26079-z. Sci Rep. 2018. PMID: 29802257 Free PMC article.
56 results