Sawyers CL - Search Results

1

Identification of multipotent luminal progenitor cells in human prostate organoid cultures.

Karthaus WR, Iaquinta PJ, Drost J, Gracanin A, van Boxtel R, Wongvipat J, Dowling CM, Gao D, Begthel H, Sachs N, Vries RGJ, Cuppen E, Chen Y, Sawyers CL, Clevers HC. Karthaus WR, et al. Among authors: sawyers cl. Cell. 2014 Sep 25;159(1):163-175. doi: 10.1016/j.cell.2014.08.017. Epub 2014 Sep 4. Cell. 2014. PMID: 25201529 Free PMC article.

2

Myc-driven murine prostate cancer shares molecular features with human prostate tumors.

Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, Matusik R, Thomas GV, Sawyers CL. Ellwood-Yen K, et al. Among authors: sawyers cl. Cancer Cell. 2003 Sep;4(3):223-38. doi: 10.1016/s1535-6108(03)00197-1. Cancer Cell. 2003. PMID: 14522256 Free article.

3

HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability.

Mellinghoff IK, Vivanco I, Kwon A, Tran C, Wongvipat J, Sawyers CL. Mellinghoff IK, et al. Among authors: sawyers cl. Cancer Cell. 2004 Nov;6(5):517-27. doi: 10.1016/j.ccr.2004.09.031. Cancer Cell. 2004. PMID: 15542435 Free article.

4

Context-dependent hormone-refractory progression revealed through characterization of a novel murine prostate cancer cell line.

Watson PA, Ellwood-Yen K, King JC, Wongvipat J, Lebeau MM, Sawyers CL. Watson PA, et al. Among authors: sawyers cl. Cancer Res. 2005 Dec 15;65(24):11565-71. doi: 10.1158/0008-5472.CAN-05-3441. Cancer Res. 2005. PMID: 16357166

5

Transgenic mouse model for rapid pharmacodynamic evaluation of antiandrogens.

Ellwood-Yen K, Wongvipat J, Sawyers C. Ellwood-Yen K, et al. Cancer Res. 2006 Nov 1;66(21):10513-6. doi: 10.1158/0008-5472.CAN-06-1397. Cancer Res. 2006. PMID: 17079473

6

Targeting the androgen receptor pathway in prostate cancer.

Chen Y, Sawyers CL, Scher HI. Chen Y, et al. Among authors: sawyers cl. Curr Opin Pharmacol. 2008 Aug;8(4):440-8. doi: 10.1016/j.coph.2008.07.005. Epub 2008 Aug 12. Curr Opin Pharmacol. 2008. PMID: 18674639 Free PMC article. Review.

7

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.

Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL. Tran C, et al. Among authors: sawyers cl. Science. 2009 May 8;324(5928):787-90. doi: 10.1126/science.1168175. Epub 2009 Apr 9. Science. 2009. PMID: 19359544 Free PMC article. Clinical Trial.

8

Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis.

King JC, Xu J, Wongvipat J, Hieronymus H, Carver BS, Leung DH, Taylor BS, Sander C, Cardiff RD, Couto SS, Gerald WL, Sawyers CL. King JC, et al. Among authors: sawyers cl. Nat Genet. 2009 May;41(5):524-6. doi: 10.1038/ng.371. Epub 2009 Apr 26. Nat Genet. 2009. PMID: 19396167 Free PMC article.

9

Finding and drugging the vulnerabilities of RAS-dependent cancers.

Sawyers CL. Sawyers CL. Cell. 2009 May 29;137(5):796-8. doi: 10.1016/j.cell.2009.05.011. Cell. 2009. PMID: 19490885 Free article.

10

Coordinate transcriptional regulation by ERG and androgen receptor in fusion-positive prostate cancers.

Chen Y, Sawyers CL. Chen Y, et al. Among authors: sawyers cl. Cancer Cell. 2010 May 18;17(5):415-6. doi: 10.1016/j.ccr.2010.04.022. Cancer Cell. 2010. PMID: 20478521 Free PMC article.

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