Vries RGJ - Search Results

1

Identification of multipotent luminal progenitor cells in human prostate organoid cultures.

Karthaus WR, Iaquinta PJ, Drost J, Gracanin A, van Boxtel R, Wongvipat J, Dowling CM, Gao D, Begthel H, Sachs N, Vries RGJ, Cuppen E, Chen Y, Sawyers CL, Clevers HC. Karthaus WR, et al. Among authors: vries rgj. Cell. 2014 Sep 25;159(1):163-175. doi: 10.1016/j.cell.2014.08.017. Epub 2014 Sep 4. Cell. 2014. PMID: 25201529 Free PMC article.

2

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Sato T, Vries RG, Snippert HJ, van de Wetering M, Barker N, Stange DE, van Es JH, Abo A, Kujala P, Peters PJ, Clevers H. Sato T, et al. Nature. 2009 May 14;459(7244):262-5. doi: 10.1038/nature07935. Epub 2009 Mar 29. Nature. 2009. PMID: 19329995

3

The kinase TNIK is an essential activator of Wnt target genes.

Mahmoudi T, Li VS, Ng SS, Taouatas N, Vries RG, Mohammed S, Heck AJ, Clevers H. Mahmoudi T, et al. EMBO J. 2009 Nov 4;28(21):3329-40. doi: 10.1038/emboj.2009.285. Epub 2009 Oct 8. EMBO J. 2009. PMID: 19816403 Free PMC article.

4

Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.

Snippert HJ, Haegebarth A, Kasper M, Jaks V, van Es JH, Barker N, van de Wetering M, van den Born M, Begthel H, Vries RG, Stange DE, Toftgård R, Clevers H. Snippert HJ, et al. Science. 2010 Mar 12;327(5971):1385-9. doi: 10.1126/science.1184733. Science. 2010. PMID: 20223988

5

Stem cells and cancer of the stomach and intestine.

Vries RG, Huch M, Clevers H. Vries RG, et al. Mol Oncol. 2010 Oct;4(5):373-84. doi: 10.1016/j.molonc.2010.05.001. Epub 2010 Jun 8. Mol Oncol. 2010. PMID: 20598659 Free PMC article. Review.

6

The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.

Mahmoudi T, Boj SF, Hatzis P, Li VS, Taouatas N, Vries RG, Teunissen H, Begthel H, Korving J, Mohammed S, Heck AJ, Clevers H. Mahmoudi T, et al. PLoS Biol. 2010 Nov 16;8(11):e1000539. doi: 10.1371/journal.pbio.1000539. PLoS Biol. 2010. PMID: 21103407 Free PMC article.

7

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.

Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H. Sato T, et al. Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28. Nature. 2011. PMID: 21113151 Free PMC article.

8

Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes.

Schepers AG, Vries R, van den Born M, van de Wetering M, Clevers H. Schepers AG, et al. EMBO J. 2011 Mar 16;30(6):1104-9. doi: 10.1038/emboj.2011.26. Epub 2011 Feb 4. EMBO J. 2011. PMID: 21297579 Free PMC article.

9

Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan.

Emmink BL, Van Houdt WJ, Vries RG, Hoogwater FJ, Govaert KM, Verheem A, Nijkamp MW, Steller EJ, Jimenez CR, Clevers H, Borel Rinkes IH, Kranenburg O. Emmink BL, et al. Gastroenterology. 2011 Jul;141(1):269-78. doi: 10.1053/j.gastro.2011.03.052. Epub 2011 Apr 1. Gastroenterology. 2011. PMID: 21459094

10

Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target.

Van Houdt WJ, Emmink BL, Pham TV, Piersma SR, Verheem A, Vries RG, Fratantoni SA, Pronk A, Clevers H, Borel Rinkes IH, Jimenez CR, Kranenburg O. Van Houdt WJ, et al. Mol Cell Proteomics. 2011 Dec;10(12):M111.011353. doi: 10.1074/mcp.M111.011353. Epub 2011 Jul 25. Mol Cell Proteomics. 2011. PMID: 21788403 Free PMC article.

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