van Boxtel R - Search Results

1

Identification of multipotent luminal progenitor cells in human prostate organoid cultures.

Karthaus WR, Iaquinta PJ, Drost J, Gracanin A, van Boxtel R, Wongvipat J, Dowling CM, Gao D, Begthel H, Sachs N, Vries RGJ, Cuppen E, Chen Y, Sawyers CL, Clevers HC. Karthaus WR, et al. Among authors: van boxtel r. Cell. 2014 Sep 25;159(1):163-175. doi: 10.1016/j.cell.2014.08.017. Epub 2014 Sep 4. Cell. 2014. PMID: 25201529 Free PMC article.

2

Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51.

Heijink AM, Stok C, Porubsky D, Manolika EM, de Kanter JK, Kok YP, Everts M, de Boer HR, Audrey A, Bakker FJ, Wierenga E, Tijsterman M, Guryev V, Spierings DCJ, Knipscheer P, van Boxtel R, Ray Chaudhuri A, Lansdorp PM, van Vugt MATM. Heijink AM, et al. Among authors: van vugt matm, van boxtel r. Nat Commun. 2022 Nov 7;13(1):6722. doi: 10.1038/s41467-022-34519-8. Nat Commun. 2022. PMID: 36344511 Free PMC article.

3

Mutation accumulation in mtDNA of cancers resembles mutagenesis in normal stem cells.

Manders F, van Dinter J, van Boxtel R. Manders F, et al. Among authors: van boxtel r, van dinter j. iScience. 2022 Nov 16;25(12):105610. doi: 10.1016/j.isci.2022.105610. eCollection 2022 Dec 22. iScience. 2022. PMID: 36458259 Free PMC article.

4

Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis.

van Boxtel R, Toonen PW, van Roekel HS, Verheul M, Smits BM, Korving J, de Bruin A, Cuppen E. van Boxtel R, et al. Among authors: van roekel hs. Carcinogenesis. 2008 Jun;29(6):1290-7. doi: 10.1093/carcin/bgn094. Epub 2008 Apr 15. Carcinogenesis. 2008. PMID: 18417481

5

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals.

van Boxtel R, Toonen PW, Verheul M, van Roekel HS, Nijman IJ, Guryev V, Cuppen E. van Boxtel R, et al. Among authors: van roekel hs. BMC Genomics. 2008 Oct 7;9:460. doi: 10.1186/1471-2164-9-460. BMC Genomics. 2008. PMID: 18840264 Free PMC article.

6

ENU mutagenesis to generate genetically modified rat models.

van Boxtel R, Gould MN, Cuppen E, Smits BM. van Boxtel R, et al. Methods Mol Biol. 2010;597:151-67. doi: 10.1007/978-1-60327-389-3_11. Methods Mol Biol. 2010. PMID: 20013232

7

Systematic generation of in vivo G protein-coupled receptor mutants in the rat.

van Boxtel R, Vroling B, Toonen P, Nijman IJ, van Roekel H, Verheul M, Baakman C, Guryev V, Vriend G, Cuppen E. van Boxtel R, et al. Among authors: van roekel h. Pharmacogenomics J. 2011 Oct;11(5):326-36. doi: 10.1038/tpj.2010.44. Epub 2010 Jun 8. Pharmacogenomics J. 2011. PMID: 20531371 Free PMC article.

8

Rat traps: filling the toolbox for manipulating the rat genome.

van Boxtel R, Cuppen E. van Boxtel R, et al. Genome Biol. 2010;11(9):217. doi: 10.1186/gb-2010-11-9-217. Epub 2010 Sep 29. Genome Biol. 2010. PMID: 20887642 Free PMC article. Review.

9

Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples.

Nijman IJ, Mokry M, van Boxtel R, Toonen P, de Bruijn E, Cuppen E. Nijman IJ, et al. Among authors: van boxtel r. Nat Methods. 2010 Nov;7(11):913-5. doi: 10.1038/nmeth.1516. Epub 2010 Oct 17. Nat Methods. 2010. PMID: 20953175

10

Generation of genetically modified rodents using random ENU mutagenesis.

van Boxtel R, Cuppen E. van Boxtel R, et al. Methods Mol Biol. 2011;693:295-308. doi: 10.1007/978-1-60761-974-1_18. Methods Mol Biol. 2011. PMID: 21080288

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