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An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington's disease.
Süssmuth SD, Haider S, Landwehrmeyer GB, Farmer R, Frost C, Tripepi G, Andersen CA, Di Bacco M, Lamanna C, Diodato E, Massai L, Diamanti D, Mori E, Magnoni L, Dreyhaupt J, Schiefele K, Craufurd D, Saft C, Rudzinska M, Ryglewicz D, Orth M, Brzozy S, Baran A, Pollio G, Andre R, Tabrizi SJ, Darpo B, Westerberg G; PADDINGTON Consortium. Süssmuth SD, et al. Among authors: andre r. Br J Clin Pharmacol. 2015 Mar;79(3):465-76. doi: 10.1111/bcp.12512. Br J Clin Pharmacol. 2015. PMID: 25223731 Free PMC article. Clinical Trial.
Biomarker development for Huntington's disease.
Andre R, Scahill RI, Haider S, Tabrizi SJ. Andre R, et al. Drug Discov Today. 2014 Jul;19(7):972-9. doi: 10.1016/j.drudis.2014.03.002. Epub 2014 Mar 12. Drug Discov Today. 2014. PMID: 24632006 Review.
Huntington's disease: fighting on many fronts.
Andre R, Wild EJ, Tabrizi SJ. Andre R, et al. Brain. 2012 Apr;135(Pt 4):998-1001. doi: 10.1093/brain/aws060. Epub 2012 Mar 16. Brain. 2012. PMID: 22427330 No abstract available.
452 results