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Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity.
Kristiansen H, Scherer CA, McVean M, Iadonato SP, Vends S, Thavachelvam K, Steffensen TB, Horan KA, Kuri T, Weber F, Paludan SR, Hartmann R. Kristiansen H, et al. Among authors: thavachelvam k. J Virol. 2010 Nov;84(22):11898-904. doi: 10.1128/JVI.01003-10. Epub 2010 Sep 15. J Virol. 2010. PMID: 20844035 Free PMC article.
Rapid Uptake and Inhibition of Viral Propagation by Extracellular OAS1.
Thavachelvam K, Gad HH, Ibsen MS, Desprès P, Hokland M, Hartmann R, Kristiansen H. Thavachelvam K, et al. J Interferon Cytokine Res. 2015 May;35(5):359-66. doi: 10.1089/jir.2014.0140. Epub 2014 Dec 17. J Interferon Cytokine Res. 2015. PMID: 25517543
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP.
Jønsson KL, Laustsen A, Krapp C, Skipper KA, Thavachelvam K, Hotter D, Egedal JH, Kjolby M, Mohammadi P, Prabakaran T, Sørensen LK, Sun C, Jensen SB, Holm CK, Lebbink RJ, Johannsen M, Nyegaard M, Mikkelsen JG, Kirchhoff F, Paludan SR, Jakobsen MR. Jønsson KL, et al. Among authors: thavachelvam k. Nat Commun. 2017 Feb 10;8:14391. doi: 10.1038/ncomms14391. Nat Commun. 2017. PMID: 28186168 Free PMC article.
Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.
Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR. Neidleman JA, et al. Among authors: thavachelvam k. PLoS Pathog. 2017 Feb 16;13(2):e1006163. doi: 10.1371/journal.ppat.1006163. eCollection 2017 Feb. PLoS Pathog. 2017. PMID: 28207890 Free PMC article.
Cell-Extrinsic Priming Increases Permissiveness of CD4+ T Cells to Human Immunodeficiency Virus Infection by Increasing C-C Chemokine Receptor Type 5 Co-receptor Expression and Cellular Activation Status.
Pedersen JG, Egedal JH, Packard TA, Thavachelvam K, Xie G, van der Sluis RM, Greene WC, Roan NR, Jakobsen MR. Pedersen JG, et al. Among authors: thavachelvam k. Front Microbiol. 2021 Nov 26;12:763030. doi: 10.3389/fmicb.2021.763030. eCollection 2021. Front Microbiol. 2021. PMID: 34899645 Free PMC article.
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