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Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm.
Li XY, MacArthur S, Bourgon R, Nix D, Pollard DA, Iyer VN, Hechmer A, Simirenko L, Stapleton M, Luengo Hendriks CL, Chu HC, Ogawa N, Inwood W, Sementchenko V, Beaton A, Weiszmann R, Celniker SE, Knowles DW, Gingeras T, Speed TP, Eisen MB, Biggin MD. Li XY, et al. PLoS Biol. 2008 Feb;6(2):e27. doi: 10.1371/journal.pbio.0060027. PLoS Biol. 2008. PMID: 18271625 Free PMC article.
Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions.
MacArthur S, Li XY, Li J, Brown JB, Chu HC, Zeng L, Grondona BP, Hechmer A, Simirenko L, Keränen SV, Knowles DW, Stapleton M, Bickel P, Biggin MD, Eisen MB. MacArthur S, et al. Among authors: li j, li xy. Genome Biol. 2009;10(7):R80. doi: 10.1186/gb-2009-10-7-r80. Epub 2009 Jul 23. Genome Biol. 2009. PMID: 19627575 Free PMC article.
Dense Bicoid hubs accentuate binding along the morphogen gradient.
Mir M, Reimer A, Haines JE, Li XY, Stadler M, Garcia H, Eisen MB, Darzacq X. Mir M, et al. Among authors: li xy. Genes Dev. 2017 Sep 1;31(17):1784-1794. doi: 10.1101/gad.305078.117. Genes Dev. 2017. PMID: 28982761 Free PMC article.
4,523 results