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Apheresis causes complement deposition on red blood cells (RBCs) and RBC antigen alterations, possibly inducing enhanced clearance.
de Back DZ, Nezjad SG, Beuger BM, Veldhuis M, Clifford E, Ait Ichou F, Berghuis J, Go M, Gouwerok E, Meinderts S, Vrielink H, de Kort W, de Korte D, van Kraaij M, van Bruggen R. de Back DZ, et al. Among authors: gouwerok e. Transfusion. 2018 Nov;58(11):2627-2634. doi: 10.1111/trf.14896. Epub 2018 Sep 28. Transfusion. 2018. PMID: 30265755
Platelet concentrates in platelet additive solutions generate less complement activation products during storage than platelets stored in plasma.
de Wit YES, Vlaar R, Gouwerok E, Hamzeh-Cognasse H, van Mierlo G, Bulder I, Lagerberg JWM, de Korte D, Cognasse F, Ten Brinke A, Zeerleder SS. de Wit YES, et al. Among authors: gouwerok e. Blood Transfus. 2023 Mar;21(2):157-167. doi: 10.2450/2022.0323-21. Epub 2022 Mar 7. Blood Transfus. 2023. PMID: 35302481 Free PMC article.
Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study.
Cognasse F, Hamzeh Cognasse H, Eyraud MA, Prier A, Arthaud CA, Tiberghien P, Begue S, de Korte D, Gouwerok E, Greinacher A, Aurich K, Noorman F, Dumont L, Kelly K, Cloutier M, Bazin R, Cardigan R, Huish S, Smethurst P, Devine D, Schubert P, Johnson L, Marks DC; Biomedical Excellence for Safer Transfusion (BEST) Collaborative. Cognasse F, et al. Among authors: gouwerok e. Transfusion. 2023 Jan;63(1):217-228. doi: 10.1111/trf.17200. Epub 2022 Dec 1. Transfusion. 2023. PMID: 36453841