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The extracellular adherence protein from Staphylococcus aureus inhibits the classical and lectin pathways of complement by blocking formation of the C3 proconvertase.
Woehl JL, Stapels DAC, Garcia BL, Ramyar KX, Keightley A, Ruyken M, Syriga M, Sfyroera G, Weber AB, Zolkiewski M, Ricklin D, Lambris JD, Rooijakkers SHM, Geisbrecht BV. Woehl JL, et al. J Immunol. 2014 Dec 15;193(12):6161-6171. doi: 10.4049/jimmunol.1401600. Epub 2014 Nov 7. J Immunol. 2014. PMID: 25381436 Free PMC article.
Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors.
Stapels DA, Ramyar KX, Bischoff M, von Köckritz-Blickwede M, Milder FJ, Ruyken M, Eisenbeis J, McWhorter WJ, Herrmann M, van Kessel KP, Geisbrecht BV, Rooijakkers SH. Stapels DA, et al. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13187-92. doi: 10.1073/pnas.1407616111. Epub 2014 Aug 26. Proc Natl Acad Sci U S A. 2014. PMID: 25161283 Free PMC article.
Neutrophil serine proteases in antibacterial defense.
Stapels DA, Geisbrecht BV, Rooijakkers SH. Stapels DA, et al. Curr Opin Microbiol. 2015 Feb;23:42-8. doi: 10.1016/j.mib.2014.11.002. Epub 2014 Nov 18. Curr Opin Microbiol. 2015. PMID: 25461571 Free PMC article. Review.
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