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Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.
Sok D, van Gils MJ, Pauthner M, Julien JP, Saye-Francisco KL, Hsueh J, Briney B, Lee JH, Le KM, Lee PS, Hua Y, Seaman MS, Moore JP, Ward AB, Wilson IA, Sanders RW, Burton DR. Sok D, et al. Among authors: lee jh, lee ps. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17624-9. doi: 10.1073/pnas.1415789111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422458 Free PMC article.
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.
Blattner C, Lee JH, Sliepen K, Derking R, Falkowska E, de la Peña AT, Cupo A, Julien JP, van Gils M, Lee PS, Peng W, Paulson JC, Poignard P, Burton DR, Moore JP, Sanders RW, Wilson IA, Ward AB. Blattner C, et al. Among authors: lee jh, lee ps. Immunity. 2014 May 15;40(5):669-80. doi: 10.1016/j.immuni.2014.04.008. Epub 2014 Apr 24. Immunity. 2014. PMID: 24768348 Free PMC article.
A common solution to group 2 influenza virus neutralization.
Friesen RH, Lee PS, Stoop EJ, Hoffman RM, Ekiert DC, Bhabha G, Yu W, Juraszek J, Koudstaal W, Jongeneelen M, Korse HJ, Ophorst C, Brinkman-van der Linden EC, Throsby M, Kwakkenbos MJ, Bakker AQ, Beaumont T, Spits H, Kwaks T, Vogels R, Ward AB, Goudsmit J, Wilson IA. Friesen RH, et al. Among authors: lee ps. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):445-50. doi: 10.1073/pnas.1319058110. Epub 2013 Dec 11. Proc Natl Acad Sci U S A. 2014. PMID: 24335589 Free PMC article.
Structure of the apo anti-influenza CH65 Fab.
Lee PS, Arnell AJ, Wilson IA. Lee PS, et al. Acta Crystallogr F Struct Biol Commun. 2015 Feb;71(Pt 2):145-8. doi: 10.1107/S2053230X14027599. Epub 2015 Jan 28. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25664786 Free PMC article.
667 results