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The PIGRET assay, a method for measuring Pig-a gene mutation in reticulocytes, is reliable as a short-term in vivo genotoxicity test: Summary of the MMS/JEMS-collaborative study across 16 laboratories using 24 chemicals.
Kimoto T, Horibata K, Miura D, Chikura S, Okada Y, Ukai A, Itoh S, Nakayama S, Sanada H, Koyama N, Muto S, Uno Y, Yamamoto M, Suzuki Y, Fukuda T, Goto K, Wada K, Kyoya T, Shigano M, Takasawa H, Hamada S, Adachi H, Uematsu Y, Tsutsumi E, Hori H, Kikuzuki R, Ogiwara Y, Yoshida I, Maeda A, Narumi K, Fujiishi Y, Morita T, Yamada M, Honma M. Kimoto T, et al. Among authors: sanada h. Mutat Res Genet Toxicol Environ Mutagen. 2016 Nov 15;811:3-15. doi: 10.1016/j.mrgentox.2016.10.003. Epub 2016 Oct 21. Mutat Res Genet Toxicol Environ Mutagen. 2016. PMID: 27931811 Free article.
Evaluation of the repeated-dose liver and gastrointestinal tract micronucleus assays with 22 chemicals using young adult rats: summary of the collaborative study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/The Japanese Environmental Mutagen Society (JEMS) - Mammalian Mutagenicity Study Group (MMS).
Hamada S, Ohyama W, Takashima R, Shimada K, Matsumoto K, Kawakami S, Uno F, Sui H, Shimada Y, Imamura T, Matsumura S, Sanada H, Inoue K, Muto S, Ogawa I, Hayashi A, Takayanagi T, Ogiwara Y, Maeda A, Okada E, Terashima Y, Takasawa H, Narumi K, Wako Y, Kawasako K, Sano M, Ohashi N, Morita T, Kojima H, Honma M, Hayashi M. Hamada S, et al. Among authors: sanada h. Mutat Res Genet Toxicol Environ Mutagen. 2015 Mar;780-781:2-17. doi: 10.1016/j.mrgentox.2015.01.001. Epub 2015 Jan 5. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25892619 Free article.
Standard protocol for the PIGRET assay, a high-throughput reticulocyte Pig-a assay with an immunomagnetic separation, used in the interlaboratory trial organized by the Mammalian Mutagenicity Study Group of the Japanese Environmental Mutagen and Genome Society.
Chikura S, Kimoto T, Itoh S, Sanada H, Muto S, Horibata K. Chikura S, et al. Among authors: sanada h. Genes Environ. 2021 Mar 20;43(1):10. doi: 10.1186/s41021-021-00181-7. Genes Environ. 2021. PMID: 33743813 Free PMC article.
750 results