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Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA.
Kootte RS, Smits LP, van der Valk FM, Dasseux JL, Keyserling CH, Barbaras R, Paolini JF, Santos RD, van Dijk TH, Dallinga-van Thie GM, Nederveen AJ, Mulder WM, Hovingh GK, Kastelein JP, Groen AK, Stroes E. Kootte RS, et al. Among authors: barbaras r. J Lipid Res. 2015 Mar;56(3):703-712. doi: 10.1194/jlr.M055665. Epub 2015 Jan 5. J Lipid Res. 2015. PMID: 25561459 Free PMC article. Clinical Trial.
HDL mimetic CER-001 targets atherosclerotic plaques in patients.
Zheng KH, van der Valk FM, Smits LP, Sandberg M, Dasseux JL, Baron R, Barbaras R, Keyserling C, Coolen BF, Nederveen AJ, Verberne HJ, Nell TE, Vugts DJ, Duivenvoorden R, Fayad ZA, Mulder WJM, van Dongen GAMS, Stroes ESG. Zheng KH, et al. Among authors: barbaras r. Atherosclerosis. 2016 Aug;251:381-388. doi: 10.1016/j.atherosclerosis.2016.05.038. Epub 2016 May 27. Atherosclerosis. 2016. PMID: 27263077 Free article.
CER-001, a HDL-mimetic, stimulates the reverse lipid transport and atherosclerosis regression in high cholesterol diet-fed LDL-receptor deficient mice.
Tardy C, Goffinet M, Boubekeur N, Ackermann R, Sy G, Bluteau A, Cholez G, Keyserling C, Lalwani N, Paolini JF, Dasseux JL, Barbaras R, Baron R. Tardy C, et al. Among authors: barbaras r. Atherosclerosis. 2014 Jan;232(1):110-8. doi: 10.1016/j.atherosclerosis.2013.10.018. Epub 2013 Nov 8. Atherosclerosis. 2014. PMID: 24401224
Non-clinical development of CER-001.
Barbaras R. Barbaras R. Front Pharmacol. 2015 Oct 6;6:220. doi: 10.3389/fphar.2015.00220. eCollection 2015. Front Pharmacol. 2015. PMID: 26500552 Free PMC article. Review.
Accelerated lipid absorption in mice overexpressing intestinal SR-BI.
Bietrix F, Yan D, Nauze M, Rolland C, Bertrand-Michel J, Coméra C, Schaak S, Barbaras R, Groen AK, Perret B, Tercé F, Collet X. Bietrix F, et al. Among authors: barbaras r. J Biol Chem. 2006 Mar 17;281(11):7214-9. doi: 10.1074/jbc.M508868200. Epub 2006 Jan 18. J Biol Chem. 2006. PMID: 16421100 Free PMC article.
P2Y13 receptor regulates HDL metabolism and atherosclerosis in vivo.
Goffinet M, Tardy C, Boubekeur N, Cholez G, Bluteau A, Oniciu DC, Lalwani ND, Dasseux JL, Barbaras R, Baron R. Goffinet M, et al. Among authors: barbaras r. PLoS One. 2014 Apr 25;9(4):e95807. doi: 10.1371/journal.pone.0095807. eCollection 2014. PLoS One. 2014. PMID: 24769858 Free PMC article.
53 results