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High-mobility group box 1 contributes to lethality of endotoxemia in heme oxygenase-1-deficient mice.
Takamiya R, Hung CC, Hall SR, Fukunaga K, Nagaishi T, Maeno T, Owen C, Macias AA, Fredenburgh LE, Ishizaka A, Blumberg RS, Baron RM, Perrella MA. Takamiya R, et al. Among authors: fredenburgh le. Am J Respir Cell Mol Biol. 2009 Aug;41(2):129-35. doi: 10.1165/rcmb.2008-0331OC. Epub 2008 Dec 18. Am J Respir Cell Mol Biol. 2009. PMID: 19097991 Free PMC article.
Inflammasome-regulated cytokines are critical mediators of acute lung injury.
Dolinay T, Kim YS, Howrylak J, Hunninghake GM, An CH, Fredenburgh L, Massaro AF, Rogers A, Gazourian L, Nakahira K, Haspel JA, Landazury R, Eppanapally S, Christie JD, Meyer NJ, Ware LB, Christiani DC, Ryter SW, Baron RM, Choi AM. Dolinay T, et al. Am J Respir Crit Care Med. 2012 Jun 1;185(11):1225-34. doi: 10.1164/rccm.201201-0003OC. Epub 2012 Mar 29. Am J Respir Crit Care Med. 2012. PMID: 22461369 Free PMC article.
Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation.
Nakahira K, Kyung SY, Rogers AJ, Gazourian L, Youn S, Massaro AF, Quintana C, Osorio JC, Wang Z, Zhao Y, Lawler LA, Christie JD, Meyer NJ, Mc Causland FR, Waikar SS, Waxman AB, Chung RT, Bueno R, Rosas IO, Fredenburgh LE, Baron RM, Christiani DC, Hunninghake GM, Choi AM. Nakahira K, et al. Among authors: fredenburgh le. PLoS Med. 2013 Dec;10(12):e1001577; discussion e1001577. doi: 10.1371/journal.pmed.1001577. Epub 2013 Dec 31. PLoS Med. 2013. PMID: 24391478 Free PMC article.
Metabolomic derangements are associated with mortality in critically ill adult patients.
Rogers AJ, McGeachie M, Baron RM, Gazourian L, Haspel JA, Nakahira K, Fredenburgh LE, Hunninghake GM, Raby BA, Matthay MA, Otero RM, Fowler VG, Rivers EP, Woods CW, Kingsmore S, Langley RJ, Choi AM. Rogers AJ, et al. Among authors: fredenburgh le. PLoS One. 2014 Jan 30;9(1):e87538. doi: 10.1371/journal.pone.0087538. eCollection 2014. PLoS One. 2014. PMID: 24498130 Free PMC article.
Integrative "omic" analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from systemic inflammatory response syndromes.
Langley RJ, Tipper JL, Bruse S, Baron RM, Tsalik EL, Huntley J, Rogers AJ, Jaramillo RJ, O'Donnell D, Mega WM, Keaton M, Kensicki E, Gazourian L, Fredenburgh LE, Massaro AF, Otero RM, Fowler VG Jr, Rivers EP, Woods CW, Kingsmore SF, Sopori ML, Perrella MA, Choi AM, Harrod KS. Langley RJ, et al. Among authors: fredenburgh le. Am J Respir Crit Care Med. 2014 Aug 15;190(4):445-55. doi: 10.1164/rccm.201404-0624OC. Am J Respir Crit Care Med. 2014. PMID: 25054455 Free PMC article.
Circadian rhythm reprogramming during lung inflammation.
Haspel JA, Chettimada S, Shaik RS, Chu JH, Raby BA, Cernadas M, Carey V, Process V, Hunninghake GM, Ifedigbo E, Lederer JA, Englert J, Pelton A, Coronata A, Fredenburgh LE, Choi AM. Haspel JA, et al. Among authors: fredenburgh le. Nat Commun. 2014 Sep 11;5:4753. doi: 10.1038/ncomms5753. Nat Commun. 2014. PMID: 25208554 Free PMC article.
Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia.
Fredenburgh LE, Kraft BD, Hess DR, Harris RS, Wolf MA, Suliman HB, Roggli VL, Davies JD, Winkler T, Stenzler A, Baron RM, Thompson BT, Choi AM, Welty-Wolf KE, Piantadosi CA. Fredenburgh LE, et al. Am J Physiol Lung Cell Mol Physiol. 2015 Oct 15;309(8):L834-46. doi: 10.1152/ajplung.00240.2015. Epub 2015 Aug 28. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 26320156 Free PMC article.
Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension.
Liu F, Haeger CM, Dieffenbach PB, Sicard D, Chrobak I, Coronata AM, Suárez Velandia MM, Vitali S, Colas RA, Norris PC, Marinković A, Liu X, Ma J, Rose CD, Lee SJ, Comhair SA, Erzurum SC, McDonald JD, Serhan CN, Walsh SR, Tschumperlin DJ, Fredenburgh LE. Liu F, et al. Among authors: fredenburgh le. JCI Insight. 2016 Jun 2;1(8):e86987. doi: 10.1172/jci.insight.86987. JCI Insight. 2016. PMID: 27347562 Free PMC article.
70 results