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AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.
Nature. 2015 Mar 5;519(7541):87-91. doi: 10.1038/nature14264. Epub 2015 Feb 18.
Nature. 2015.
PMID: 25707797
Free PMC article.
CD4-Induced Antibodies Promote Association of the HIV-1 Envelope Glycoprotein with CD4-Binding Site Antibodies.
Gardner MR, Fellinger CH, Prasad NR, Zhou AS, Kondur HR, Joshi VR, Quinlan BD, Farzan M.
Gardner MR, et al. Among authors: fellinger ch.
J Virol. 2016 Aug 12;90(17):7822-32. doi: 10.1128/JVI.00803-16. Print 2016 Sep 1.
J Virol. 2016.
PMID: 27334589
Free PMC article.
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Simian Immunodeficiency Virus SIVmac239, but Not SIVmac316, Binds and Utilizes Human CD4 More Efficiently than Rhesus CD4.
Fellinger CH, Gardner MR, Bailey CC, Farzan M.
Fellinger CH, et al.
J Virol. 2017 Aug 24;91(18):e00847-17. doi: 10.1128/JVI.00847-17. Print 2017 Sep 15.
J Virol. 2017.
PMID: 28679752
Free PMC article.
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eCD4-Ig Limits HIV-1 Escape More Effectively than CD4-Ig or a Broadly Neutralizing Antibody.
Fellinger CH, Gardner MR, Weber JA, Alfant B, Zhou AS, Farzan M.
Fellinger CH, et al.
J Virol. 2019 Jun 28;93(14):e00443-19. doi: 10.1128/JVI.00443-19. Print 2019 Jul 15.
J Virol. 2019.
PMID: 31068428
Free PMC article.
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AAV-delivered eCD4-Ig protects rhesus macaques from high-dose SIVmac239 challenges.
Gardner MR, Fellinger CH, Kattenhorn LM, Davis-Gardner ME, Weber JA, Alfant B, Zhou AS, Prasad NR, Kondur HR, Newton WA, Weisgrau KL, Rakasz EG, Lifson JD, Gao G, Schultz-Darken N, Farzan M.
Gardner MR, et al. Among authors: fellinger ch.
Sci Transl Med. 2019 Jul 24;11(502):eaau5409. doi: 10.1126/scitranslmed.aau5409.
Sci Transl Med. 2019.
PMID: 31341061
Free PMC article.
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Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
Wensel D, Williams S, Dixon DP, Ward P, McCormick P, Concha N, Stewart E, Hong X, Mazzucco C, Pal S, Ding B, Fellinger C, Krystal M.
Wensel D, et al.
J Mol Biol. 2022 Jan 30;434(2):167395. doi: 10.1016/j.jmb.2021.167395. Epub 2021 Dec 9.
J Mol Biol. 2022.
PMID: 34896364
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