Ross CA - Search Results

1

HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.

Mattis VB, Tom C, Akimov S, Saeedian J, Østergaard ME, Southwell AL, Doty CN, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Arjomand J, Hayden MR, Ross CA, Svendsen CN. Mattis VB, et al. Among authors: ross ca. Hum Mol Genet. 2015 Jun 1;24(11):3257-71. doi: 10.1093/hmg/ddv080. Epub 2015 Mar 3. Hum Mol Genet. 2015. PMID: 25740845 Free PMC article.

2

Human-induced pluripotent stem cells: potential for neurodegenerative diseases.

Ross CA, Akimov SS. Ross CA, et al. Hum Mol Genet. 2014 Sep 15;23(R1):R17-26. doi: 10.1093/hmg/ddu204. Epub 2014 May 13. Hum Mol Genet. 2014. PMID: 24824217 Free PMC article. Review.

3

Bioenergetic deficits in Huntington's disease iPSC-derived neural cells and rescue with glycolytic metabolites.

HD iPSC Consortium. HD iPSC Consortium. Hum Mol Genet. 2020 Jul 21;29(11):1757-1771. doi: 10.1093/hmg/ddy430. Hum Mol Genet. 2020. PMID: 30768179 Free PMC article.

4

Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor.

Eddings CR, Arbez N, Akimov S, Geva M, Hayden MR, Ross CA. Eddings CR, et al. Among authors: ross ca. Neurobiol Dis. 2019 Sep;129:118-129. doi: 10.1016/j.nbd.2019.05.009. Epub 2019 May 17. Neurobiol Dis. 2019. PMID: 31108174 Free PMC article.

5

Immortalized striatal precursor neurons from Huntington's disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics.

Akimov SS, Jiang M, Kedaigle AJ, Arbez N, Marque LO, Eddings CR, Ranum PT, Whelan E, Tang A, Wang R, DeVine LR, Talbot CC, Cole RN, Ratovitski T, Davidson BL, Fraenkel E, Ross CA. Akimov SS, et al. Among authors: ross ca. Hum Mol Genet. 2021 Nov 30;30(24):2469-2487. doi: 10.1093/hmg/ddab200. Hum Mol Genet. 2021. PMID: 34296279 Free PMC article.

6

Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcript.

Goldberg YP, Kalchman MA, Metzler M, Nasir J, Zeisler J, Graham R, Koide HB, O'Kusky J, Sharp AH, Ross CA, Jirik F, Hayden MR. Goldberg YP, et al. Among authors: ross ca. Hum Mol Genet. 1996 Feb;5(2):177-85. doi: 10.1093/hmg/5.2.177. Hum Mol Genet. 1996. PMID: 8824873

7

Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior.

Chan EY, Nasir J, Gutekunst CA, Coleman S, Maclean A, Maas A, Metzler M, Gertsenstein M, Ross CA, Nagy A, Hayden MR. Chan EY, et al. Among authors: ross ca. Hum Mol Genet. 2002 Apr 15;11(8):945-59. doi: 10.1093/hmg/11.8.945. Hum Mol Genet. 2002. PMID: 11971876

8

pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model.

Xu X, Ng B, Sim B, Radulescu CI, Yusof NABM, Goh WI, Lin S, Lim JSY, Cha Y, Kusko R, Kay C, Ratovitski T, Ross C, Hayden MR, Wright G, Pouladi MA. Xu X, et al. Cell Death Dis. 2020 Sep 25;11(9):809. doi: 10.1038/s41419-020-02983-z. Cell Death Dis. 2020. PMID: 32978366 Free PMC article.

9

Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease.

Jiang M, Peng Q, Liu X, Jin J, Hou Z, Zhang J, Mori S, Ross CA, Ye K, Duan W. Jiang M, et al. Among authors: ross ca. Hum Mol Genet. 2013 Jun 15;22(12):2462-70. doi: 10.1093/hmg/ddt098. Epub 2013 Feb 27. Hum Mol Genet. 2013. PMID: 23446639 Free PMC article.

10

Cysteamine Protects Neurons from Mutant Huntingtin Toxicity.

Arbez N, Roby E, Akimov S, Eddings C, Ren M, Wang X, Ross CA. Arbez N, et al. Among authors: ross ca. J Huntingtons Dis. 2019;8(2):129-143. doi: 10.3233/JHD-180312. J Huntingtons Dis. 2019. PMID: 30856117 Free PMC article.

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