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A protein tertiary structure mimetic modulator of the Hippo signalling pathway.
Adihou H, Gopalakrishnan R, Förster T, Guéret SM, Gasper R, Geschwindner S, Carrillo García C, Karatas H, Pobbati AV, Vazquez-Chantada M, Davey P, Wassvik CM, Pang JKS, Soh BS, Hong W, Chiarparin E, Schade D, Plowright AT, Valeur E, Lemurell M, Grossmann TN, Waldmann H. Adihou H, et al. Among authors: plowright at. Nat Commun. 2020 Oct 27;11(1):5425. doi: 10.1038/s41467-020-19224-8. Nat Commun. 2020. PMID: 33110077 Free PMC article.
Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments.
Guéret SM, Thavam S, Carbajo RJ, Potowski M, Larsson N, Dahl G, Dellsén A, Grossmann TN, Plowright AT, Valeur E, Lemurell M, Waldmann H. Guéret SM, et al. Among authors: plowright at. J Am Chem Soc. 2020 Mar 11;142(10):4904-4915. doi: 10.1021/jacs.0c00269. Epub 2020 Mar 2. J Am Chem Soc. 2020. PMID: 32058716 Free PMC article.
Medicinal Chemistry Approaches to Heart Regeneration.
Schade D, Plowright AT. Schade D, et al. Among authors: plowright at. J Med Chem. 2015 Dec 24;58(24):9451-79. doi: 10.1021/acs.jmedchem.5b00446. Epub 2015 Sep 3. J Med Chem. 2015. PMID: 26288266 Review.
New Modalities for Challenging Targets in Drug Discovery.
Valeur E, Guéret SM, Adihou H, Gopalakrishnan R, Lemurell M, Waldmann H, Grossmann TN, Plowright AT. Valeur E, et al. Among authors: plowright at. Angew Chem Int Ed Engl. 2017 Aug 21;56(35):10294-10323. doi: 10.1002/anie.201611914. Epub 2017 Jul 24. Angew Chem Int Ed Engl. 2017. PMID: 28186380 Review.
Directing evolution: the next revolution in drug discovery?
Davis AM, Plowright AT, Valeur E. Davis AM, et al. Among authors: plowright at. Nat Rev Drug Discov. 2017 Oct;16(10):681-698. doi: 10.1038/nrd.2017.146. Epub 2017 Sep 22. Nat Rev Drug Discov. 2017. PMID: 28935911 Review.
Emerging modes-of-action in drug discovery.
Valeur E, Narjes F, Ottmann C, Plowright AT. Valeur E, et al. Among authors: plowright at. Medchemcomm. 2019 Jun 25;10(9):1550-1568. doi: 10.1039/c9md00263d. eCollection 2019 Sep 1. Medchemcomm. 2019. PMID: 31673315 Free PMC article. Review.
Joining Forces: The Chemical Biology-Medicinal Chemistry Continuum.
Plowright AT, Ottmann C, Arkin M, Auberson YP, Timmerman H, Waldmann H. Plowright AT, et al. Cell Chem Biol. 2017 Sep 21;24(9):1058-1065. doi: 10.1016/j.chembiol.2017.05.019. Epub 2017 Jun 8. Cell Chem Biol. 2017. PMID: 28602761 Free article. Review.
46 results