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A novel Alzheimer disease locus located near the gene encoding tau protein.
Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH Jr, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L; IGAP Consortium; Haines JL, Psaty BM, Van … See abstract for full author list ➔ Jun G, et al. Among authors: holmans p. Mol Psychiatry. 2016 Jan;21(1):108-17. doi: 10.1038/mp.2015.23. Epub 2015 Mar 17. Mol Psychiatry. 2016. PMID: 25778476 Free PMC article.
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.
Moskvina V, Craddock N, Holmans P, Nikolov I, Pahwa JS, Green E; Wellcome Trust Case Control Consortium; Owen MJ, O'Donovan MC. Moskvina V, et al. Among authors: holmans p. Mol Psychiatry. 2009 Mar;14(3):252-60. doi: 10.1038/mp.2008.133. Epub 2008 Dec 9. Mol Psychiatry. 2009. PMID: 19065143 Free PMC article.
Genome-wide association study of Alzheimer's disease with psychotic symptoms.
Hollingworth P, Sweet R, Sims R, Harold D, Russo G, Abraham R, Stretton A, Jones N, Gerrish A, Chapman J, Ivanov D, Moskvina V, Lovestone S, Priotsi P, Lupton M, Brayne C, Gill M, Lawlor B, Lynch A, Craig D, McGuinness B, Johnston J, Holmes C, Livingston G, Bass NJ, Gurling H, McQuillin A; GERAD Consortium; National Institute on Aging Late-Onset Alzheimer's Disease Family Study Group; Holmans P, Jones L, Devlin B, Klei L, Barmada MM, Demirci FY, DeKosky ST, Lopez OL, Passmore P, Owen MJ, O'Donovan MC, Mayeux R, Kamboh MI, Williams J. Hollingworth P, et al. Among authors: holmans p. Mol Psychiatry. 2012 Dec;17(12):1316-27. doi: 10.1038/mp.2011.125. Epub 2011 Oct 18. Mol Psychiatry. 2012. PMID: 22005930 Free PMC article.
Common alleles contribute to schizophrenia in CNV carriers.
Tansey KE, Rees E, Linden DE, Ripke S, Chambert KD, Moran JL, McCarroll SA, Holmans P, Kirov G, Walters J, Owen MJ, O'Donovan MC. Tansey KE, et al. Among authors: holmans p. Mol Psychiatry. 2016 Aug;21(8):1085-9. doi: 10.1038/mp.2015.143. Epub 2015 Sep 22. Mol Psychiatry. 2016. PMID: 26390827 Free PMC article.
Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.
Craddock N, Jones L, Jones IR, Kirov G, Green EK, Grozeva D, Moskvina V, Nikolov I, Hamshere ML, Vukcevic D, Caesar S, Gordon-Smith K, Fraser C, Russell E, Norton N, Breen G, St Clair D, Collier DA, Young AH, Ferrier IN, Farmer A, McGuffin P, Holmans PA; Wellcome Trust Case Control Consortium (WTCCC); Donnelly P, Owen MJ, O'Donovan MC. Craddock N, et al. Among authors: holmans pa. Mol Psychiatry. 2010 Feb;15(2):146-53. doi: 10.1038/mp.2008.66. Epub 2008 Jul 1. Mol Psychiatry. 2010. PMID: 19078961 Free PMC article.
Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms.
Holmans PA, Riley B, Pulver AE, Owen MJ, Wildenauer DB, Gejman PV, Mowry BJ, Laurent C, Kendler KS, Nestadt G, Williams NM, Schwab SG, Sanders AR, Nertney D, Mallet J, Wormley B, Lasseter VK, O'Donovan MC, Duan J, Albus M, Alexander M, Godard S, Ribble R, Liang KY, Norton N, Maier W, Papadimitriou G, Walsh D, Jay M, O'Neill A, Lerer FB, Dikeos D, Crowe RR, Silverman JM, Levinson DF. Holmans PA, et al. Mol Psychiatry. 2009 Aug;14(8):786-95. doi: 10.1038/mp.2009.11. Epub 2009 Feb 17. Mol Psychiatry. 2009. PMID: 19223858 Free PMC article.
Meta-analysis of 32 genome-wide linkage studies of schizophrenia.
Ng MY, Levinson DF, Faraone SV, Suarez BK, DeLisi LE, Arinami T, Riley B, Paunio T, Pulver AE, Irmansyah, Holmans PA, Escamilla M, Wildenauer DB, Williams NM, Laurent C, Mowry BJ, Brzustowicz LM, Maziade M, Sklar P, Garver DL, Abecasis GR, Lerer B, Fallin MD, Gurling HM, Gejman PV, Lindholm E, Moises HW, Byerley W, Wijsman EM, Forabosco P, Tsuang MT, Hwu HG, Okazaki Y, Kendler KS, Wormley B, Fanous A, Walsh D, O'Neill FA, Peltonen L, Nestadt G, Lasseter VK, Liang KY, Papadimitriou GM, Dikeos DG, Schwab SG, Owen MJ, O'Donovan MC, Norton N, Hare E, Raventos H, Nicolini H, Albus M, Maier W, Nimgaonkar VL, Terenius L, Mallet J, Jay M, Godard S, Nertney D, Alexander M, Crowe RR, Silverman JM, Bassett AS, Roy MA, Mérette C, Pato CN, Pato MT, Roos JL, Kohn Y, Amann-Zalcenstein D, Kalsi G, McQuillin A, Curtis D, Brynjolfson J, Sigmundsson T, Petursson H, Sanders AR, Duan J, Jazin E, Myles-Worsley M, Karayiorgou M, Lewis CM. Ng MY, et al. Among authors: holmans pa. Mol Psychiatry. 2009 Aug;14(8):774-85. doi: 10.1038/mp.2008.135. Epub 2008 Dec 30. Mol Psychiatry. 2009. PMID: 19349958 Free PMC article.
Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.
Lips ES, Cornelisse LN, Toonen RF, Min JL, Hultman CM; International Schizophrenia Consortium; Holmans PA, O'Donovan MC, Purcell SM, Smit AB, Verhage M, Sullivan PF, Visscher PM, Posthuma D. Lips ES, et al. Among authors: holmans pa. Mol Psychiatry. 2012 Oct;17(10):996-1006. doi: 10.1038/mp.2011.117. Epub 2011 Sep 20. Mol Psychiatry. 2012. PMID: 21931320 Free PMC article.
440 results