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ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation.
Alemdehy MF, Haanstra JR, de Looper HW, van Strien PM, Verhagen-Oldenampsen J, Caljouw Y, Sanders MA, Hoogenboezem R, de Ru AH, Janssen GM, Smetsers SE, Bierings MB, van Veelen PA, von Lindern M, Touw IP, Erkeland SJ. Alemdehy MF, et al. Blood. 2015 Jun 18;125(25):3937-48. doi: 10.1182/blood-2014-11-612507. Epub 2015 Mar 16. Blood. 2015. PMID: 25778535 Free article.
MicroRNA-155 induces AML in combination with the loss of C/EBPA in mice.
Alemdehy MF, de Looper HW, Kavelaars FG, Sanders MA, Hoogenboezem R, Löwenberg B, Valk PJ, Touw IP, Erkeland SJ. Alemdehy MF, et al. Leukemia. 2016 Nov;30(11):2238-2241. doi: 10.1038/leu.2016.171. Epub 2016 Jun 4. Leukemia. 2016. PMID: 27363282 No abstract available.
Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors.
Wojtowicz EE, Lechman ER, Hermans KG, Schoof EM, Wienholds E, Isserlin R, van Veelen PA, Broekhuis MJ, Janssen GM, Trotman-Grant A, Dobson SM, Krivdova G, Elzinga J, Kennedy J, Gan OI, Sinha A, Ignatchenko V, Kislinger T, Dethmers-Ausema B, Weersing E, Alemdehy MF, de Looper HW, Bader GD, Ritsema M, Erkeland SJ, Bystrykh LV, Dick JE, de Haan G. Wojtowicz EE, et al. Among authors: alemdehy mf. Cell Stem Cell. 2016 Sep 1;19(3):383-96. doi: 10.1016/j.stem.2016.06.008. Epub 2016 Jul 14. Cell Stem Cell. 2016. PMID: 27424784 Free PMC article.
Towards an understanding of C9orf82 protein/CAAP1 function.
Aslam MA, Alemdehy MF, Pritchard CEJ, Song JY, Muhaimin FI, Wijdeven RH, Huijbers IJ, Neefjes J, Jacobs H. Aslam MA, et al. Among authors: alemdehy mf. PLoS One. 2019 Jan 10;14(1):e0210526. doi: 10.1371/journal.pone.0210526. eCollection 2019. PLoS One. 2019. PMID: 30629682 Free PMC article.
Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology.
Telford BJ, Yahyanejad S, de Gunst T, den Boer HC, Vos RM, Stegink M, van den Bosch MTJ, Alemdehy MF, van Pinxteren LAH, Schaapveld RQJ, Janicot M. Telford BJ, et al. Among authors: alemdehy mf. Oncotarget. 2021 Mar 2;12(5):422-439. doi: 10.18632/oncotarget.27894. eCollection 2021 Mar 2. Oncotarget. 2021. PMID: 33747358 Free PMC article.
The Ig heavy chain protein but not its message controls early B cell development.
Aslam MA, Alemdehy MF, Hao B, Krijger PHL, Pritchard CEJ, de Rink I, Muhaimin FI, Nurzijah I, van Baalen M, Kerkhoven RM, van den Berk PCM, Skok JA, Jacobs H. Aslam MA, et al. Among authors: alemdehy mf. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31343-31352. doi: 10.1073/pnas.2004810117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229554 Free PMC article.
Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation.
Aslam MA, Alemdehy MF, Kwesi-Maliepaard EM, Muhaimin FI, Caganova M, Pardieck IN, van den Brand T, van Welsem T, de Rink I, Song JY, de Wit E, Arens R, Jacobs H, van Leeuwen F. Aslam MA, et al. Among authors: alemdehy mf. EMBO Rep. 2021 Feb 3;22(2):e51184. doi: 10.15252/embr.202051184. Epub 2021 Jan 7. EMBO Rep. 2021. PMID: 33410591 Free PMC article.
14 results