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Eliminating antibody polyreactivity through addition of N-linked glycosylation.
Chuang GY, Zhang B, McKee K, O'Dell S, Kwon YD, Zhou T, Blinn J, Lloyd K, Parks R, Von Holle T, Ko SY, Kong WP, Pegu A, Wang K, Baruah K, Crispin M, Mascola JR, Moody MA, Haynes BF, Georgiev IS, Kwong PD. Chuang GY, et al. Among authors: crispin m. Protein Sci. 2015 Jun;24(6):1019-30. doi: 10.1002/pro.2682. Epub 2015 May 12. Protein Sci. 2015. PMID: 25800131 Free PMC article.
Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity.
Ackerman ME, Crispin M, Yu X, Baruah K, Boesch AW, Harvey DJ, Dugast AS, Heizen EL, Ercan A, Choi I, Streeck H, Nigrovic PA, Bailey-Kellogg C, Scanlan C, Alter G. Ackerman ME, et al. Among authors: crispin m. J Clin Invest. 2013 May;123(5):2183-92. doi: 10.1172/JCI65708. Epub 2013 Apr 8. J Clin Invest. 2013. PMID: 23563315 Free PMC article.
Fragments of bacterial endoglycosidase s and immunoglobulin g reveal subdomains of each that contribute to deglycosylation.
Dixon EV, Claridge JK, Harvey DJ, Baruah K, Yu X, Vesiljevic S, Mattick S, Pritchard LK, Krishna B, Scanlan CN, Schnell JR, Higgins MK, Zitzmann N, Crispin M. Dixon EV, et al. Among authors: crispin m. J Biol Chem. 2014 May 16;289(20):13876-89. doi: 10.1074/jbc.M113.532812. Epub 2014 Mar 25. J Biol Chem. 2014. PMID: 24668806 Free PMC article.
228 results