Filizola M - Search Results

1

αIIbβ3 variants defined by next-generation sequencing: predicting variants likely to cause Glanzmann thrombasthenia.

Buitrago L, Rendon A, Liang Y, Simeoni I, Negri A; ThromboGenomics Consortium; Filizola M, Ouwehand WH, Coller BS. Buitrago L, et al. Among authors: filizola m. Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):E1898-907. doi: 10.1073/pnas.1422238112. Epub 2015 Mar 31. Proc Natl Acad Sci U S A. 2015. PMID: 25827233 Free PMC article.

2

Structural basis for partial agonism in 5-HT_3A receptors.

Felt K, Stauffer M, Salas-Estrada L, Guzzo PR, Xie D, Huang J, Filizola M, Chakrapani S. Felt K, et al. Among authors: filizola m. Nat Struct Mol Biol. 2024 Apr;31(4):598-609. doi: 10.1038/s41594-023-01140-2. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177669

3

Mechanistic insights from a refined three-dimensional model of integrin alphaIIbbeta3.

Filizola M, Hassan SA, Artoni A, Coller BS, Weinstein H. Filizola M, et al. J Biol Chem. 2004 Jun 4;279(23):24624-30. doi: 10.1074/jbc.M400243200. Epub 2004 Mar 30. J Biol Chem. 2004. PMID: 15056669 Free article.

4

Functional and computational studies of the ligand-associated metal binding site of beta3 integrins.

Murcia M, Jirouskova M, Li J, Coller BS, Filizola M. Murcia M, et al. Among authors: filizola m. Proteins. 2008 Jun;71(4):1779-91. doi: 10.1002/prot.21859. Proteins. 2008. PMID: 18175315 Free PMC article.

5

Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel alphaIIb-specific alphaIIbbeta3 antagonist.

Blue R, Kowalska MA, Hirsch J, Murcia M, Janczak CA, Harrington A, Jirouskova M, Li J, Fuentes R, Thornton MA, Filizola M, Poncz M, Coller BS. Blue R, et al. Among authors: filizola m. Blood. 2009 Jul 2;114(1):195-201. doi: 10.1182/blood-2008-08-169243. Epub 2009 May 4. Blood. 2009. PMID: 19414864 Free PMC article.

6

Targeted molecular dynamics reveals overall common conformational changes upon hybrid domain swing-out in beta3 integrins.

Provasi D, Murcia M, Coller BS, Filizola M. Provasi D, et al. Among authors: filizola m. Proteins. 2009 Nov 1;77(2):477-89. doi: 10.1002/prot.22463. Proteins. 2009. PMID: 19455709 Free PMC article.

7

Effects of limiting extension at the alphaIIb genu on ligand binding to integrin alphaIIbbeta3.

Blue R, Li J, Steinberger J, Murcia M, Filizola M, Coller BS. Blue R, et al. Among authors: filizola m. J Biol Chem. 2010 Jun 4;285(23):17604-13. doi: 10.1074/jbc.M110.107763. Epub 2010 Apr 2. J Biol Chem. 2010. PMID: 20363746 Free PMC article.

8

Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening.

Zhu J, Zhu J, Negri A, Provasi D, Filizola M, Coller BS, Springer TA. Zhu J, et al. Among authors: filizola m. Blood. 2010 Dec 2;116(23):5050-9. doi: 10.1182/blood-2010-04-281154. Epub 2010 Aug 2. Blood. 2010. PMID: 20679525 Free PMC article.

9

Ligand-induced modulation of the free-energy landscape of G protein-coupled receptors explored by adaptive biasing techniques.

Provasi D, Artacho MC, Negri A, Mobarec JC, Filizola M. Provasi D, et al. Among authors: filizola m. PLoS Comput Biol. 2011 Oct;7(10):e1002193. doi: 10.1371/journal.pcbi.1002193. Epub 2011 Oct 13. PLoS Comput Biol. 2011. PMID: 22022248 Free PMC article.

10

Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.

Zhu J, Choi WS, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D, Rasmussen M, Aster R, Thomas CJ, Filizola M, Springer TA, Coller BS. Zhu J, et al. Among authors: filizola m. Sci Transl Med. 2012 Mar 14;4(125):125ra32. doi: 10.1126/scitranslmed.3003576. Sci Transl Med. 2012. PMID: 22422993 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

127 results

Search Page