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Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.
Bettaieb A, Jiang JX, Sasaki Y, Chao TI, Kiss Z, Chen X, Tian J, Katsuyama M, Yabe-Nishimura C, Xi Y, Szyndralewiez C, Schröder K, Shah A, Brandes RP, Haj FG, Török NJ. Bettaieb A, et al. Among authors: tian j. Gastroenterology. 2015 Aug;149(2):468-80.e10. doi: 10.1053/j.gastro.2015.04.009. Epub 2015 Apr 14. Gastroenterology. 2015. PMID: 25888330 Free PMC article.
Galectin 3 regulates HCC cell invasion by RhoA and MLCK activation.
Serizawa N, Tian J, Fukada H, Baghy K, Scott F, Chen X, Kiss Z, Olson K, Hsu D, Liu FT, Török NJ, Zhao B, Jiang JX. Serizawa N, et al. Among authors: tian j. Lab Invest. 2015 Oct;95(10):1145-56. doi: 10.1038/labinvest.2015.77. Epub 2015 Jul 6. Lab Invest. 2015. PMID: 26146960 Free PMC article.
Galectin-3 regulates inflammasome activation in cholestatic liver injury.
Tian J, Yang G, Chen HY, Hsu DK, Tomilov A, Olson KA, Dehnad A, Fish SR, Cortopassi G, Zhao B, Liu FT, Gershwin ME, Török NJ, Jiang JX. Tian J, et al. FASEB J. 2016 Dec;30(12):4202-4213. doi: 10.1096/fj.201600392RR. Epub 2016 Sep 14. FASEB J. 2016. PMID: 27630169 Free PMC article.
These studies provide a rationale to target Gal3 in autoimmune cholangitis and potentially other cholestatic diseases.-Tian, J., Yang, G., Chen, H.-Y., Hsu, D. K., Tomilov, A., Olson, K. ...R., Cortopassi, G., Zhao, B., Liu, F.-T., Gershwin, M. E., Torok, N. J …
These studies provide a rationale to target Gal3 in autoimmune cholangitis and potentially other cholestatic diseases.-Tian, J …
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