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Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines.
Suijker J, Oosting J, Koornneef A, Struys EA, Salomons GS, Schaap FG, Waaijer CJ, Wijers-Koster PM, Briaire-de Bruijn IH, Haazen L, Riester SM, Dudakovic A, Danen E, Cleton-Jansen AM, van Wijnen AJ, Bovée JV. Suijker J, et al. Oncotarget. 2015 May 20;6(14):12505-19. doi: 10.18632/oncotarget.3723. Oncotarget. 2015. PMID: 25895133 Free PMC article.
Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors.
Hoekstra AS, de Graaff MA, Briaire-de Bruijn IH, Ras C, Seifar RM, van Minderhout I, Cornelisse CJ, Hogendoorn PC, Breuning MH, Suijker J, Korpershoek E, Kunst HP, Frizzell N, Devilee P, Bayley JP, Bovée JV. Hoekstra AS, et al. Among authors: suijker j. Oncotarget. 2015 Nov 17;6(36):38777-88. doi: 10.18632/oncotarget.6091. Oncotarget. 2015. PMID: 26472283 Free PMC article.
Inhibition of Bcl-2 family members sensitizes mesenchymal chondrosarcoma to conventional chemotherapy: report on a novel mesenchymal chondrosarcoma cell line.
de Jong Y, van Maldegem AM, Marino-Enriquez A, de Jong D, Suijker J, Briaire-de Bruijn IH, Kruisselbrink AB, Cleton-Jansen AM, Szuhai K, Gelderblom H, Fletcher JA, Bovée JV. de Jong Y, et al. Among authors: suijker j. Lab Invest. 2016 Oct;96(10):1128-37. doi: 10.1038/labinvest.2016.91. Epub 2016 Sep 12. Lab Invest. 2016. PMID: 27617402 Free article.
IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas.
Cleven AHG, Suijker J, Agrogiannis G, Briaire-de Bruijn IH, Frizzell N, Hoekstra AS, Wijers-Koster PM, Cleton-Jansen AM, Bovée JVMG. Cleven AHG, et al. Among authors: suijker j. Clin Sarcoma Res. 2017 May 4;7:8. doi: 10.1186/s13569-017-0074-6. eCollection 2017. Clin Sarcoma Res. 2017. PMID: 28484589 Free PMC article.
Proteasomal insensitivity of apoptin in tumor cells.
Lanz HL, Suijker J, Noteborn MH, Backendorf C. Lanz HL, et al. Among authors: suijker j. Biochem Biophys Res Commun. 2012 May 25;422(1):169-73. doi: 10.1016/j.bbrc.2012.04.132. Epub 2012 Apr 30. Biochem Biophys Res Commun. 2012. PMID: 22575449
Phenotypic screening in Organ-on-a-Chip systems: a 1537 kinase inhibitor library screen on a 3D angiogenesis assay.
Soragni C, Queiroz K, Ng CP, Stok A, Olivier T, Tzagkaraki D, Heijmans J, Suijker J, de Ruiter SPM, Olczyk A, Bokkers M, Schavemaker F, Trietsch SJ, Lanz HL, Vulto P, Joore J. Soragni C, et al. Among authors: suijker j. Angiogenesis. 2024 Feb;27(1):37-49. doi: 10.1007/s10456-023-09888-3. Epub 2023 Jul 26. Angiogenesis. 2024. PMID: 37493987 Free PMC article.
32 results