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Pandemic H1N1 2009 influenza A virus induces weak cytokine responses in human macrophages and dendritic cells and is highly sensitive to the antiviral actions of interferons.
Osterlund P, Pirhonen J, Ikonen N, Rönkkö E, Strengell M, Mäkelä SM, Broman M, Hamming OJ, Hartmann R, Ziegler T, Julkunen I. Osterlund P, et al. Among authors: julkunen i. J Virol. 2010 Feb;84(3):1414-22. doi: 10.1128/JVI.01619-09. Epub 2009 Nov 25. J Virol. 2010. PMID: 19939920 Free PMC article.
RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: dependence on TRAF2 and TAK1.
Mikkelsen SS, Jensen SB, Chiliveru S, Melchjorsen J, Julkunen I, Gaestel M, Arthur JS, Flavell RA, Ghosh S, Paludan SR. Mikkelsen SS, et al. Among authors: julkunen i. J Biol Chem. 2009 Apr 17;284(16):10774-82. doi: 10.1074/jbc.M807272200. Epub 2009 Feb 18. J Biol Chem. 2009. PMID: 19224920 Free PMC article.
264 results