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Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation.
Anggakusuma, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, Pietschmann T, Steinmann E. Anggakusuma, et al. Among authors: colpitts cc. Hepatology. 2015 Sep;62(3):702-14. doi: 10.1002/hep.27913. Epub 2015 Jul 28. Hepatology. 2015. PMID: 25999047
Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry.
Behrendt P, Perin P, Menzel N, Banda D, Pfaender S, Alves MP, Thiel V, Meuleman P, Colpitts CC, Schang LM, Vondran FWR, Anggakusuma, Manns MP, Steinmann E, Pietschmann T. Behrendt P, et al. Among authors: colpitts cc. Antiviral Res. 2017 Nov;147:19-28. doi: 10.1016/j.antiviral.2017.09.006. Epub 2017 Sep 18. Antiviral Res. 2017. PMID: 28923507
Hepatitis C virus exploits cyclophilin A to evade PKR.
Colpitts CC, Ridewood S, Schneiderman B, Warne J, Tabata K, Ng CF, Bartenschlager R, Selwood DL, Towers GJ. Colpitts CC, et al. Elife. 2020 Jun 16;9:e52237. doi: 10.7554/eLife.52237. Elife. 2020. PMID: 32539931 Free PMC article.
Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped viruses.
St Vincent MR, Colpitts CC, Ustinov AV, Muqadas M, Joyce MA, Barsby NL, Epand RF, Epand RM, Khramyshev SA, Valueva OA, Korshun VA, Tyrrell DL, Schang LM. St Vincent MR, et al. Among authors: colpitts cc. Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17339-44. doi: 10.1073/pnas.1010026107. Epub 2010 Sep 7. Proc Natl Acad Sci U S A. 2010. PMID: 20823220 Free PMC article.
A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses.
Verrier ER, Colpitts CC, Bach C, Heydmann L, Weiss A, Renaud M, Durand SC, Habersetzer F, Durantel D, Abou-Jaoudé G, López Ledesma MM, Felmlee DJ, Soumillon M, Croonenborghs T, Pochet N, Nassal M, Schuster C, Brino L, Sureau C, Zeisel MB, Baumert TF. Verrier ER, et al. Among authors: colpitts cc. Hepatology. 2016 Jan;63(1):35-48. doi: 10.1002/hep.28013. Epub 2015 Oct 6. Hepatology. 2016. PMID: 26224662
50 results