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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.
N Engl J Med. 2015 Jun 25;372(26):2509-20. doi: 10.1056/NEJMoa1500596. Epub 2015 May 30.
N Engl J Med. 2015.
PMID: 26028255
Free PMC article.
Clinical Trial.
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.
Le DT, Durham JN, Smith KN, Wang H, Bartlett BR, Aulakh LK, Lu S, Kemberling H, Wilt C, Luber BS, Wong F, Azad NS, Rucki AA, Laheru D, Donehower R, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Greten TF, Duffy AG, Ciombor KK, Eyring AD, Lam BH, Joe A, Kang SP, Holdhoff M, Danilova L, Cope L, Meyer C, Zhou S, Goldberg RM, Armstrong DK, Bever KM, Fader AN, Taube J, Housseau F, Spetzler D, Xiao N, Pardoll DM, Papadopoulos N, Kinzler KW, Eshleman JR, Vogelstein B, Anders RA, Diaz LA Jr.
Le DT, et al. Among authors: kemberling h.
Science. 2017 Jul 28;357(6349):409-413. doi: 10.1126/science.aan6733. Epub 2017 Jun 8.
Science. 2017.
PMID: 28596308
Free PMC article.
Clinical Trial.
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Anti-PD-1 elicits regression of undifferentiated pleomorphic sarcomas with UV-mutation signatures.
Cheung LS, Chen L, Oke TF, Schaffer TB, Boudadi K, Ngo JT, Gross JM, Kemberling H, Diaz LA, Lipson E, Sidhom JW, Taube J, Anders R, Pardoll DM, Le DT, Meyer CF, Llosa N.
Cheung LS, et al. Among authors: kemberling h.
J Immunother Cancer. 2021 Jun;9(6):e002345. doi: 10.1136/jitc-2021-002345.
J Immunother Cancer. 2021.
PMID: 34103354
Free PMC article.
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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of gastrointestinal cancer.
Kelly RJ, Bever K, Chao J, Ciombor KK, Eng C, Fakih M, Goyal L, Hubbard J, Iyer R, Kemberling HT, Krishnamurthi S, Ku G, Mordecai MM, Morris VK 2nd, Paulson AS, Peterson V, Shah MA, Le DT.
Kelly RJ, et al. Among authors: kemberling ht.
J Immunother Cancer. 2023 Jun;11(6):e006658. doi: 10.1136/jitc-2022-006658.
J Immunother Cancer. 2023.
PMID: 37286304
Free PMC article.
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