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Structure-Activity Relationships of the Antimicrobial Peptide Natural Product Apidaecin.
Skowron KJ, Baliga C, Johnson T, Kremiller KM, Castroverde A, Dean TT, Allen AC, Lopez-Hernandez AM, Aleksandrova EV, Klepacki D, Mankin AS, Polikanov YS, Moore TW. Skowron KJ, et al. Among authors: polikanov ys. J Med Chem. 2023 Sep 14;66(17):11831-11842. doi: 10.1021/acs.jmedchem.3c00406. Epub 2023 Aug 21. J Med Chem. 2023. PMID: 37603874 Free PMC article.
Inhibition of translation termination by the antimicrobial peptide Drosocin.
Mangano K, Klepacki D, Ohanmu I, Baliga C, Huang W, Brakel A, Krizsan A, Polikanov YS, Hoffmann R, Vázquez-Laslop N, Mankin AS. Mangano K, et al. Among authors: polikanov ys. Nat Chem Biol. 2023 Sep;19(9):1082-1090. doi: 10.1038/s41589-023-01300-x. Epub 2023 Mar 30. Nat Chem Biol. 2023. PMID: 36997647 Free PMC article.
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Phelps GA, Cheramie MN, Fernando DM, Selchow P, Meyer CJ, Waidyarachchi SL, Dharuman S, Liu J, Meuli M, Molin MD, Killam BY, Murphy PA, Reeve SM, Wilt LA, Anderson SM, Yang L, Lee RB, Temrikar ZH, Lukka PB, Meibohm B, Polikanov YS, Hobbie SN, Böttger EC, Sander P, Lee RE. Phelps GA, et al. Among authors: polikanov ys. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2314101120. doi: 10.1073/pnas.2314101120. Epub 2024 Jan 2. Proc Natl Acad Sci U S A. 2024. PMID: 38165935 Free PMC article.
Elements of ribosomal drug resistance and specificity.
Blaha GM, Polikanov YS, Steitz TA. Blaha GM, et al. Among authors: polikanov ys. Curr Opin Struct Biol. 2012 Dec;22(6):750-8. doi: 10.1016/j.sbi.2012.07.016. Epub 2012 Sep 13. Curr Opin Struct Biol. 2012. PMID: 22981944 Free PMC article. Review.
63 results