Steitz TA - Search Results

1

Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.

Polikanov YS, Starosta AL, Juette MF, Altman RB, Terry DS, Lu W, Burnett BJ, Dinos G, Reynolds KA, Blanchard SC, Steitz TA, Wilson DN. Polikanov YS, et al. Among authors: steitz ta. Mol Cell. 2015 Jun 4;58(5):832-44. doi: 10.1016/j.molcel.2015.04.014. Epub 2015 May 28. Mol Cell. 2015. PMID: 26028538 Free PMC article.

2

The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.

Bulkley D, Brandi L, Polikanov YS, Fabbretti A, O'Connor M, Gualerzi CO, Steitz TA. Bulkley D, et al. Among authors: steitz ta. Cell Rep. 2014 Jan 30;6(2):357-65. doi: 10.1016/j.celrep.2013.12.024. Epub 2014 Jan 9. Cell Rep. 2014. PMID: 24412368 Free PMC article.

3

A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.

Polikanov YS, Steitz TA, Innis CA. Polikanov YS, et al. Among authors: steitz ta. Nat Struct Mol Biol. 2014 Sep;21(9):787-93. doi: 10.1038/nsmb.2871. Epub 2014 Aug 17. Nat Struct Mol Biol. 2014. PMID: 25132179 Free PMC article.

4

Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.

Polikanov YS, Osterman IA, Szal T, Tashlitsky VN, Serebryakova MV, Kusochek P, Bulkley D, Malanicheva IA, Efimenko TA, Efremenkova OV, Konevega AL, Shaw KJ, Bogdanov AA, Rodnina MV, Dontsova OA, Mankin AS, Steitz TA, Sergiev PV. Polikanov YS, et al. Among authors: steitz ta. Mol Cell. 2014 Nov 20;56(4):531-40. doi: 10.1016/j.molcel.2014.09.020. Epub 2014 Oct 9. Mol Cell. 2014. PMID: 25306919 Free PMC article.

5

Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA.

Polikanov YS, Szal T, Jiang F, Gupta P, Matsuda R, Shiozuka M, Steitz TA, Vázquez-Laslop N, Mankin AS. Polikanov YS, et al. Among authors: steitz ta. Mol Cell. 2014 Nov 20;56(4):541-50. doi: 10.1016/j.molcel.2014.09.021. Epub 2014 Oct 9. Mol Cell. 2014. PMID: 25306922 Free PMC article.

6

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.

Polikanov YS, Melnikov SV, Söll D, Steitz TA. Polikanov YS, et al. Among authors: steitz ta. Nat Struct Mol Biol. 2015 Apr;22(4):342-344. doi: 10.1038/nsmb.2992. Epub 2015 Mar 16. Nat Struct Mol Biol. 2015. PMID: 25775268 Free PMC article.

7

How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.

Polikanov YS, Blaha GM, Steitz TA. Polikanov YS, et al. Among authors: steitz ta. Science. 2012 May 18;336(6083):915-8. doi: 10.1126/science.1218538. Science. 2012. PMID: 22605777 Free PMC article.

8

Elements of ribosomal drug resistance and specificity.

Blaha GM, Polikanov YS, Steitz TA. Blaha GM, et al. Among authors: steitz ta. Curr Opin Struct Biol. 2012 Dec;22(6):750-8. doi: 10.1016/j.sbi.2012.07.016. Epub 2012 Sep 13. Curr Opin Struct Biol. 2012. PMID: 22981944 Free PMC article. Review.

9

Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.

Melnikov SV, Söll D, Steitz TA, Polikanov YS. Melnikov SV, et al. Among authors: steitz ta. Nucleic Acids Res. 2016 Jun 2;44(10):4978-87. doi: 10.1093/nar/gkw246. Epub 2016 Apr 13. Nucleic Acids Res. 2016. PMID: 27079977 Free PMC article.

10

Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design.

Lin J, Zhou D, Steitz TA, Polikanov YS, Gagnon MG. Lin J, et al. Among authors: steitz ta. Annu Rev Biochem. 2018 Jun 20;87:451-478. doi: 10.1146/annurev-biochem-062917-011942. Epub 2018 Mar 23. Annu Rev Biochem. 2018. PMID: 29570352 Free PMC article. Review.

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