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Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis.
Villa F, Carrizzo A, Spinelli CC, Ferrario A, Malovini A, Maciąg A, Damato A, Auricchio A, Spinetti G, Sangalli E, Dang Z, Madonna M, Ambrosio M, Sitia L, Bigini P, Calì G, Schreiber S, Perls T, Fucile S, Mulas F, Nebel A, Bellazzi R, Madeddu P, Vecchione C, Puca AA. Villa F, et al. Among authors: auricchio a. Circ Res. 2015 Jul 31;117(4):333-45. doi: 10.1161/CIRCRESAHA.117.305875. Epub 2015 Jun 1. Circ Res. 2015. PMID: 26034043 Free PMC article.
A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.
Vecchione C, Villa F, Carrizzo A, Spinelli CC, Damato A, Ambrosio M, Ferrario A, Madonna M, Uccellatore A, Lupini S, Maciag A, Ryskalin L, Milanesi L, Frati G, Sciarretta S, Bellazzi R, Genovese S, Ceriello A, Auricchio A, Malovini A, Puca AA. Vecchione C, et al. Among authors: auricchio a. Sci Rep. 2017 Aug 29;7(1):9706. doi: 10.1038/s41598-017-10341-x. Sci Rep. 2017. PMID: 28852218 Free PMC article.
Author Correction: A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.
Vecchione C, Villa F, Carrizzo A, Spinelli CC, Damato A, Ambrosio M, Ferrario A, Madonna M, Uccellatore A, Lupini S, Maciag A, Ryskalin L, Milanesi L, Frati G, Sciarretta S, Bellazzi R, Genovese S, Ceriello A, Auricchio A, Malovini A, Puca AA. Vecchione C, et al. Among authors: auricchio a. Sci Rep. 2019 Jun 28;9(1):9574. doi: 10.1038/s41598-019-45691-1. Sci Rep. 2019. PMID: 31249326 Free PMC article.
Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism.
Puca AA, Carrizzo A, Spinelli C, Damato A, Ambrosio M, Villa F, Ferrario A, Maciag A, Fornai F, Lenzi P, Valenti V, di Nonno F, Accarino G, Madonna M, Forte M, Calì G, Baragetti A, Norata GD, Catapano AL, Cattaneo M, Izzo R, Trimarco V, Montella F, Versaci F, Auricchio A, Frati G, Sciarretta S, Madeddu P, Ciaglia E, Vecchione C. Puca AA, et al. Among authors: auricchio a. Eur Heart J. 2020 Jul 7;41(26):2487-2497. doi: 10.1093/eurheartj/ehz459. Eur Heart J. 2020. PMID: 31289820 Free PMC article.
The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum-microglia crosstalk preventing disease progression in a mouse model of Huntington's disease.
Di Pardo A, Ciaglia E, Cattaneo M, Maciag A, Montella F, Lopardo V, Ferrario A, Villa F, Madonna M, Amico E, Carrizzo A, Damato A, Pepe G, Marracino F, Auricchio A, Vecchione C, Maglione V, Puca AA. Di Pardo A, et al. Among authors: auricchio a. Cell Death Dis. 2020 Jul 18;11(7):546. doi: 10.1038/s41419-020-02754-w. Cell Death Dis. 2020. PMID: 32683420 Free PMC article.
Ocular gene therapy: current progress and future prospects.
Colella P, Cotugno G, Auricchio A. Colella P, et al. Among authors: auricchio a. Trends Mol Med. 2009 Jan;15(1):23-31. doi: 10.1016/j.molmed.2008.11.003. Epub 2008 Dec 25. Trends Mol Med. 2009. PMID: 19097940 Review.
Single delivery of an adeno-associated viral construct to transfer the CASQ2 gene to knock-in mice affected by catecholaminergic polymorphic ventricular tachycardia is able to cure the disease from birth to advanced age.
Denegri M, Bongianino R, Lodola F, Boncompagni S, De Giusti VC, Avelino-Cruz JE, Liu N, Persampieri S, Curcio A, Esposito F, Pietrangelo L, Marty I, Villani L, Moyaho A, Baiardi P, Auricchio A, Protasi F, Napolitano C, Priori SG. Denegri M, et al. Among authors: auricchio a. Circulation. 2014 Jun 24;129(25):2673-81. doi: 10.1161/CIRCULATIONAHA.113.006901. Epub 2014 Jun 2. Circulation. 2014. PMID: 24888331 Free article.
Allele-Specific Silencing of Mutant mRNA Rescues Ultrastructural and Arrhythmic Phenotype in Mice Carriers of the R4496C Mutation in the Ryanodine Receptor Gene (RYR2).
Bongianino R, Denegri M, Mazzanti A, Lodola F, Vollero A, Boncompagni S, Fasciano S, Rizzo G, Mangione D, Barbaro S, Di Fonso A, Napolitano C, Auricchio A, Protasi F, Priori SG. Bongianino R, et al. Among authors: auricchio a. Circ Res. 2017 Aug 18;121(5):525-536. doi: 10.1161/CIRCRESAHA.117.310882. Epub 2017 Jun 15. Circ Res. 2017. PMID: 28620067
708 results