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Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis.
Villa F, Carrizzo A, Spinelli CC, Ferrario A, Malovini A, Maciąg A, Damato A, Auricchio A, Spinetti G, Sangalli E, Dang Z, Madonna M, Ambrosio M, Sitia L, Bigini P, Calì G, Schreiber S, Perls T, Fucile S, Mulas F, Nebel A, Bellazzi R, Madeddu P, Vecchione C, Puca AA. Villa F, et al. Among authors: madeddu p. Circ Res. 2015 Jul 31;117(4):333-45. doi: 10.1161/CIRCRESAHA.117.305875. Epub 2015 Jun 1. Circ Res. 2015. PMID: 26034043 Free PMC article.
Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway.
Dang Z, Avolio E, Thomas AC, Faulkner A, Beltrami AP, Cervellin C, Carrizzo A, Maciag A, Gu Y, Ciaglia E, Finato N, Damato A, Spinetti G, Alenzi A, Paisey SJ, Vecchione C, Puca AA, Madeddu P. Dang Z, et al. Among authors: madeddu p. Eur J Heart Fail. 2020 Sep;22(9):1568-1581. doi: 10.1002/ejhf.1840. Epub 2020 May 8. Eur J Heart Fail. 2020. PMID: 32384208 Free PMC article.
Neurotrophin p75 receptor (p75NTR) promotes endothelial cell apoptosis and inhibits angiogenesis: implications for diabetes-induced impaired neovascularization in ischemic limb muscles.
Caporali A, Pani E, Horrevoets AJ, Kraenkel N, Oikawa A, Sala-Newby GB, Meloni M, Cristofaro B, Graiani G, Leroyer AS, Boulanger CM, Spinetti G, Yoon SO, Madeddu P, Emanueli C. Caporali A, et al. Among authors: madeddu p. Circ Res. 2008 Jul 18;103(2):e15-26. doi: 10.1161/CIRCRESAHA.108.177386. Epub 2008 Jun 19. Circ Res. 2008. PMID: 18566344 Free PMC article.
Tissue kallikrein is essential for invasive capacity of circulating proangiogenic cells.
Spinetti G, Fortunato O, Cordella D, Portararo P, Kränkel N, Katare R, Sala-Newby GB, Richer C, Vincent MP, Alhenc-Gelas F, Tonolo G, Cherchi S, Emanueli C, Madeddu P. Spinetti G, et al. Among authors: madeddu p. Circ Res. 2011 Feb 4;108(3):284-93. doi: 10.1161/CIRCRESAHA.110.236786. Epub 2010 Dec 16. Circ Res. 2011. PMID: 21164105 Free PMC article.
MicroRNA-15a and microRNA-16 impair human circulating proangiogenic cell functions and are increased in the proangiogenic cells and serum of patients with critical limb ischemia.
Spinetti G, Fortunato O, Caporali A, Shantikumar S, Marchetti M, Meloni M, Descamps B, Floris I, Sangalli E, Vono R, Faglia E, Specchia C, Pintus G, Madeddu P, Emanueli C. Spinetti G, et al. Among authors: madeddu p. Circ Res. 2013 Jan 18;112(2):335-46. doi: 10.1161/CIRCRESAHA.111.300418. Epub 2012 Dec 11. Circ Res. 2013. PMID: 23233752 Free PMC article. Clinical Trial.
Global remodeling of the vascular stem cell niche in bone marrow of diabetic patients: implication of the microRNA-155/FOXO3a signaling pathway.
Spinetti G, Cordella D, Fortunato O, Sangalli E, Losa S, Gotti A, Carnelli F, Rosa F, Riboldi S, Sessa F, Avolio E, Beltrami AP, Emanueli C, Madeddu P. Spinetti G, et al. Among authors: madeddu p. Circ Res. 2013 Feb 1;112(3):510-22. doi: 10.1161/CIRCRESAHA.112.300598. Epub 2012 Dec 18. Circ Res. 2013. PMID: 23250986 Free PMC article.
339 results