Lock RB - Search Results

1

AKR1C3 is a biomarker of sensitivity to PR-104 in preclinical models of T-cell acute lymphoblastic leukemia.

Moradi Manesh D, El-Hoss J, Evans K, Richmond J, Toscan CE, Bracken LS, Hedrick A, Sutton R, Marshall GM, Wilson WR, Kurmasheva RT, Billups C, Houghton PJ, Smith MA, Carol H, Lock RB. Moradi Manesh D, et al. Among authors: lock rb. Blood. 2015 Sep 3;126(10):1193-202. doi: 10.1182/blood-2014-12-618900. Epub 2015 Jun 26. Blood. 2015. PMID: 26116659 Free PMC article.

2

MRP1 gene expression level regulates the death and differentiation response of neuroblastoma cells.

Peaston AE, Gardaneh M, Franco AV, Hocker JE, Murphy KM, Farnsworth ML, Catchpoole DR, Haber M, Norris MD, Lock RB, Marshall GM. Peaston AE, et al. Among authors: lock rb. Br J Cancer. 2001 Nov 16;85(10):1564-71. doi: 10.1054/bjoc.2001.2144. Br J Cancer. 2001. PMID: 11720446 Free PMC article.

3

The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse.

Lock RB, Liem N, Farnsworth ML, Milross CG, Xue C, Tajbakhsh M, Haber M, Norris MD, Marshall GM, Rice AM. Lock RB, et al. Blood. 2002 Jun 1;99(11):4100-8. doi: 10.1182/blood.v99.11.4100. Blood. 2002. PMID: 12010813 Free article.

4

Testing of new agents in childhood cancer preclinical models: meeting summary.

Houghton PJ, Adamson PC, Blaney S, Fine HA, Gorlick R, Haber M, Helman L, Hirschfeld S, Hollingshead MG, Israel MA, Lock RB, Maris JM, Merlino G, Patterson W, Reynolds CP, Shannon K, Yu A, Yu J, Smith MA. Houghton PJ, et al. Among authors: lock rb. Clin Cancer Res. 2002 Dec;8(12):3646-57. Clin Cancer Res. 2002. PMID: 12473573

5

Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies.

Liem NL, Papa RA, Milross CG, Schmid MA, Tajbakhsh M, Choi S, Ramirez CD, Rice AM, Haber M, Norris MD, MacKenzie KL, Lock RB. Liem NL, et al. Among authors: lock rb. Blood. 2004 May 15;103(10):3905-14. doi: 10.1182/blood-2003-08-2911. Epub 2004 Feb 5. Blood. 2004. PMID: 14764536 Free article.

6

Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor.

Bachmann PS, Gorman R, Mackenzie KL, Lutze-Mann L, Lock RB. Bachmann PS, et al. Among authors: lock rb. Blood. 2005 Mar 15;105(6):2519-26. doi: 10.1182/blood-2004-05-2023. Epub 2004 Nov 30. Blood. 2005. PMID: 15572593 Free article.

7

Preclinical testing of antileukemic drugs using an in vivo model of systemic disease.

Lock RB, Liem NL, Papa RA. Lock RB, et al. Methods Mol Med. 2005;111:323-34. doi: 10.1385/1-59259-889-7:323. Methods Mol Med. 2005. PMID: 15911988

8

The pediatric preclinical testing program: description of models and early testing results.

Houghton PJ, Morton CL, Tucker C, Payne D, Favours E, Cole C, Gorlick R, Kolb EA, Zhang W, Lock R, Carol H, Tajbakhsh M, Reynolds CP, Maris JM, Courtright J, Keir ST, Friedman HS, Stopford C, Zeidner J, Wu J, Liu T, Billups CA, Khan J, Ansher S, Zhang J, Smith MA. Houghton PJ, et al. Pediatr Blood Cancer. 2007 Dec;49(7):928-40. doi: 10.1002/pbc.21078. Pediatr Blood Cancer. 2007. PMID: 17066459

9

Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis.

Whiteford CC, Bilke S, Greer BT, Chen Q, Braunschweig TA, Cenacchi N, Wei JS, Smith MA, Houghton P, Morton C, Reynolds CP, Lock R, Gorlick R, Khanna C, Thiele CJ, Takikita M, Catchpoole D, Hewitt SM, Khan J. Whiteford CC, et al. Cancer Res. 2007 Jan 1;67(1):32-40. doi: 10.1158/0008-5472.CAN-06-0610. Cancer Res. 2007. PMID: 17210681

10

Initial testing (stage 1) of the proteasome inhibitor bortezomib by the pediatric preclinical testing program.

Houghton PJ, Morton CL, Kolb EA, Lock R, Carol H, Reynolds CP, Keshelava N, Maris JM, Keir ST, Wu J, Smith MA. Houghton PJ, et al. Pediatr Blood Cancer. 2008 Jan;50(1):37-45. doi: 10.1002/pbc.21214. Pediatr Blood Cancer. 2008. PMID: 17420992

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