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Host cell mTORC1 is required for HCV RNA replication.
Stöhr S, Costa R, Sandmann L, Westhaus S, Pfaender S, Anggakusuma, Dazert E, Meuleman P, Vondran FW, Manns MP, Steinmann E, von Hahn T, Ciesek S. Stöhr S, et al. Among authors: dazert e. Gut. 2016 Dec;65(12):2017-2028. doi: 10.1136/gutjnl-2014-308971. Epub 2015 Aug 14. Gut. 2016. PMID: 26276683 Free PMC article.
mTOR signaling in disease.
Dazert E, Hall MN. Dazert E, et al. Curr Opin Cell Biol. 2011 Dec;23(6):744-55. doi: 10.1016/j.ceb.2011.09.003. Epub 2011 Sep 29. Curr Opin Cell Biol. 2011. PMID: 21963299 Review.
mTORC2 Promotes Tumorigenesis via Lipid Synthesis.
Guri Y, Colombi M, Dazert E, Hindupur SK, Roszik J, Moes S, Jenoe P, Heim MH, Riezman I, Riezman H, Hall MN. Guri Y, et al. Among authors: dazert e. Cancer Cell. 2017 Dec 11;32(6):807-823.e12. doi: 10.1016/j.ccell.2017.11.011. Cancer Cell. 2017. PMID: 29232555 Free article.
Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.
Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, Timm J, McKiernan S, Kelleher D, Gruener N, Tavis JE, Rosen HR, Shaw J, Bowness P, Blum HE, Klenerman P, Bartenschlager R, Thimme R. Dazert E, et al. J Clin Invest. 2009 Feb;119(2):376-86. doi: 10.1172/JCI36587. Epub 2009 Jan 12. J Clin Invest. 2009. PMID: 19139562 Free PMC article.
Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection.
Ruggieri A, Dazert E, Metz P, Hofmann S, Bergeest JP, Mazur J, Bankhead P, Hiet MS, Kallis S, Alvisi G, Samuel CE, Lohmann V, Kaderali L, Rohr K, Frese M, Stoecklin G, Bartenschlager R. Ruggieri A, et al. Among authors: dazert e. Cell Host Microbe. 2012 Jul 19;12(1):71-85. doi: 10.1016/j.chom.2012.05.013. Cell Host Microbe. 2012. PMID: 22817989 Free PMC article.
Proteomic Landscape of Aldosterone-Producing Adenoma.
Swierczynska MM, Betz MJ, Colombi M, Dazert E, Jenö P, Moes S, Pfaff C, Glatz K, Reincke M, Beuschlein F, Donath MY, Hall MN. Swierczynska MM, et al. Among authors: dazert e. Hypertension. 2019 Feb;73(2):469-480. doi: 10.1161/HYPERTENSIONAHA.118.11733. Hypertension. 2019. PMID: 30580688 Free article.
LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function.
Tang F, Gao R, Jeevan-Raj B, Wyss CB, Kalathur RKR, Piscuoglio S, Ng CKY, Hindupur SK, Nuciforo S, Dazert E, Bock T, Song S, Buechel D, Morini MF, Hergovich A, Matthias P, Lim DS, Terracciano LM, Heim MH, Hall MN, Christofori G. Tang F, et al. Among authors: dazert e. Nat Commun. 2019 Dec 17;10(1):5755. doi: 10.1038/s41467-019-13591-7. Nat Commun. 2019. PMID: 31848340 Free PMC article.
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