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A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Impagliazzo A, Milder F, Kuipers H, Wagner MV, Zhu X, Hoffman RM, van Meersbergen R, Huizingh J, Wanningen P, Verspuij J, de Man M, Ding Z, Apetri A, Kükrer B, Sneekes-Vriese E, Tomkiewicz D, Laursen NS, Lee PS, Zakrzewska A, Dekking L, Tolboom J, Tettero L, van Meerten S, Yu W, Koudstaal W, Goudsmit J, Ward AB, Meijberg W, Wilson IA, Radošević K. Impagliazzo A, et al. Among authors: hoffman rm. Science. 2015 Sep 18;349(6254):1301-6. doi: 10.1126/science.aac7263. Epub 2015 Aug 24. Science. 2015. PMID: 26303961
Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Laursen NS, Friesen RHE, Zhu X, Jongeneelen M, Blokland S, Vermond J, van Eijgen A, Tang C, van Diepen H, Obmolova G, van der Neut Kolfschoten M, Zuijdgeest D, Straetemans R, Hoffman RMB, Nieusma T, Pallesen J, Turner HL, Bernard SM, Ward AB, Luo J, Poon LLM, Tretiakova AP, Wilson JM, Limberis MP, Vogels R, Brandenburg B, Kolkman JA, Wilson IA. Laursen NS, et al. Science. 2018 Nov 2;362(6414):598-602. doi: 10.1126/science.aaq0620. Science. 2018. PMID: 30385580 Free PMC article.
A common solution to group 2 influenza virus neutralization.
Friesen RH, Lee PS, Stoop EJ, Hoffman RM, Ekiert DC, Bhabha G, Yu W, Juraszek J, Koudstaal W, Jongeneelen M, Korse HJ, Ophorst C, Brinkman-van der Linden EC, Throsby M, Kwakkenbos MJ, Bakker AQ, Beaumont T, Spits H, Kwaks T, Vogels R, Ward AB, Goudsmit J, Wilson IA. Friesen RH, et al. Among authors: hoffman rm. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):445-50. doi: 10.1073/pnas.1319058110. Epub 2013 Dec 11. Proc Natl Acad Sci U S A. 2014. PMID: 24335589 Free PMC article.
DNA-Binding Agent Trabectedin Combined With Recombinant Methioninase Is Synergistic to Decrease Fibrosarcoma Cell Viability and Induce Nuclear Fragmentation But Not Synergistic on Normal Fibroblasts.
Morinaga S, Han Q, Kubota Y, Mizuta K, Kang BM, Sato M, Bouvet M, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Higuchi T, Tsuchiya H, Demura S, Hoffman RM. Morinaga S, et al. Among authors: hoffman rm. Anticancer Res. 2024 Jun;44(6):2359-2367. doi: 10.21873/anticanres.17043. Anticancer Res. 2024. PMID: 38821601
The potential of methioninase for cancer treatment.
Abo Qoura L, Balakin KV, Hoffman RM, Pokrovsky VS. Abo Qoura L, et al. Among authors: hoffman rm. Biochim Biophys Acta Rev Cancer. 2024 May 23;1879(4):189122. doi: 10.1016/j.bbcan.2024.189122. Online ahead of print. Biochim Biophys Acta Rev Cancer. 2024. PMID: 38796027 Review.
The TELEhealth Shared decision-making Coaching and Navigation in Primary carE (TELESCOPE) intervention: a study protocol for delivering shared decision-making for lung cancer screening by patient navigators.
Tan NQP, Lowenstein LM, Douglas EE, Silva J, Bershad JM, An J, Shete SS, Steinberg MB, Ferrante JM, Clark EC, Natale-Pereira A, Sahu NN, Hastings SE, Hoffman RM, Volk RJ, Kinney AY. Tan NQP, et al. Among authors: hoffman rm. Res Sq [Preprint]. 2024 Apr 22:rs.3.rs-4254047. doi: 10.21203/rs.3.rs-4254047/v1. Res Sq. 2024. PMID: 38746205 Free PMC article. Preprint.
Efficacy of Recombinant Methioninase on Late-stage Patient Cancer in the Histoculture Drug Response Assay (HDRA) as a Potential Functional Biomarker of Sensitivity to Methionine-restriction Therapy in the Clinic.
Kubota Y, Sasaki M, Han Q, Hozumi C, Tsunoda T, Hoffman RM. Kubota Y, et al. Among authors: hoffman rm. Cancer Diagn Progn. 2024 May 3;4(3):239-243. doi: 10.21873/cdp.10314. eCollection 2024 May-Jun. Cancer Diagn Progn. 2024. PMID: 38707720 Free PMC article. Review.
1,477 results