Martinez ED - Search Results

1

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1.

Schneider P, Bayo-Fina JM, Singh R, Kumar Dhanyamraju P, Holz P, Baier A, Fendrich V, Ramaswamy A, Baumeister S, Martinez ED, Lauth M. Schneider P, et al. Among authors: martinez ed. Nat Commun. 2015 Aug 27;6:8023. doi: 10.1038/ncomms9023. Nat Commun. 2015. PMID: 26310823 Free PMC article.

2

Corrigendum: identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1.

Schneider P, Bayo-Fina JM, Singh R, Dhanyamraju PK, Holz P, Baier A, Fendrich V, Ramaswamy A, Baumeister S, Martinez ED, Lauth M. Schneider P, et al. Among authors: martinez ed. Nat Commun. 2015 Oct 26;6:8741. doi: 10.1038/ncomms9741. Nat Commun. 2015. PMID: 26498676 Free PMC article. No abstract available.

3

A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth.

Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Peña-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, Easmon J, Martinez ED. Wang L, et al. Among authors: martinez ed. Nat Commun. 2013;4:2035. doi: 10.1038/ncomms3035. Nat Commun. 2013. PMID: 23792809 Free PMC article.

4

Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis.

Zhang QJ, Tran TAT, Wang M, Ranek MJ, Kokkonen-Simon KM, Gao J, Luo X, Tan W, Kyrychenko V, Liao L, Xu J, Hill JA, Olson EN, Kass DA, Martinez ED, Liu ZP. Zhang QJ, et al. Among authors: martinez ed. Nat Commun. 2018 Dec 7;9(1):5230. doi: 10.1038/s41467-018-07173-2. Nat Commun. 2018. PMID: 30531796 Free PMC article.

5

Epigenetic modulation reveals differentiation state specificity of oncogene addiction.

Khaliq M, Manikkam M, Martinez ED, Fallahi-Sichani M. Khaliq M, et al. Among authors: martinez ed. Nat Commun. 2021 Mar 9;12(1):1536. doi: 10.1038/s41467-021-21784-2. Nat Commun. 2021. PMID: 33750776 Free PMC article.

6

Inhibiting the Jumonji family: a potential new clinical approach to targeting aberrant epigenetic mechanisms.

Martinez ED, Gazdar AF. Martinez ED, et al. Epigenomics. 2016 Mar;8(3):313-6. doi: 10.2217/epi.15.115. Epub 2016 Feb 26. Epigenomics. 2016. PMID: 26918824 No abstract available.

7

KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes.

Duan L, Rai G, Roggero C, Zhang QJ, Wei Q, Ma SH, Zhou Y, Santoyo J, Martinez ED, Xiao G, Raj GV, Jadhav A, Simeonov A, Maloney DJ, Rizo J, Hsieh JT, Liu ZP. Duan L, et al. Among authors: martinez ed. Chem Biol. 2015 Sep 17;22(9):1185-96. doi: 10.1016/j.chembiol.2015.08.007. Epub 2015 Sep 10. Chem Biol. 2015. PMID: 26364928 Free PMC article.

8

Inhibition of Jumonji demethylases reprograms severe dilated cardiomyopathy and prolongs survival.

Tran TA, Zhang QJ, Wang L, Gonzales C, Girard L, May H, Gillette T, Liu ZP, Martinez ED. Tran TA, et al. Among authors: martinez ed. J Biol Chem. 2022 Feb;298(2):101515. doi: 10.1016/j.jbc.2021.101515. Epub 2021 Dec 18. J Biol Chem. 2022. PMID: 34933013 Free PMC article.

9

Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases.

Matthews KA, Senagbe KM, Nötzel C, Gonzales CA, Tong X, Rijo-Ferreira F, Bhanu NV, Miguel-Blanco C, Lafuente-Monasterio MJ, Garcia BA, Kafsack BFC, Martinez ED. Matthews KA, et al. Among authors: martinez ed. ACS Infect Dis. 2020 May 8;6(5):1058-1075. doi: 10.1021/acsinfecdis.9b00455. Epub 2020 Apr 24. ACS Infect Dis. 2020. PMID: 32272012 Free PMC article.

10

Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks.

Bayo J, Tran TA, Wang L, Peña-Llopis S, Das AK, Martinez ED. Bayo J, et al. Among authors: martinez ed. Cell Rep. 2018 Oct 23;25(4):1040-1050.e5. doi: 10.1016/j.celrep.2018.09.081. Cell Rep. 2018. PMID: 30355483 Free PMC article.

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