Charrier S - Search Results

1

Lymphopoiesis in transgenic mice over-expressing Artemis.

Rivera-Munoz P, Abramowski V, Jacquot S, André P, Charrier S, Lipson-Ruffert K, Fischer A, Galy A, Cavazzana M, de Villartay JP. Rivera-Munoz P, et al. Among authors: charrier s. Gene Ther. 2016 Feb;23(2):176-86. doi: 10.1038/gt.2015.95. Epub 2015 Oct 1. Gene Ther. 2016. PMID: 26361272

2

A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice.

Charrier S, Stockholm D, Seye K, Opolon P, Taveau M, Gross DA, Bucher-Laurent S, Delenda C, Vainchenker W, Danos O, Galy A. Charrier S, et al. Gene Ther. 2005 Apr;12(7):597-606. doi: 10.1038/sj.gt.3302440. Gene Ther. 2005. PMID: 15616597

3

Biosafety Studies of a Clinically Applicable Lentiviral Vector for the Gene Therapy of Artemis-SCID.

Charrier S, Lagresle-Peyrou C, Poletti V, Rothe M, Cédrone G, Gjata B, Mavilio F, Fischer A, Schambach A, de Villartay JP, Cavazzana M, Hacein-Bey-Abina S, Galy A. Charrier S, et al. Mol Ther Methods Clin Dev. 2019 Sep 13;15:232-245. doi: 10.1016/j.omtm.2019.08.014. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31720302 Free PMC article.

4

Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients.

Charrier S, Dupré L, Scaramuzza S, Jeanson-Leh L, Blundell MP, Danos O, Cattaneo F, Aiuti A, Eckenberg R, Thrasher AJ, Roncarolo MG, Galy A. Charrier S, et al. Gene Ther. 2007 Mar;14(5):415-28. doi: 10.1038/sj.gt.3302863. Epub 2006 Oct 19. Gene Ther. 2007. PMID: 17051251

5

Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: application to the gene therapy of WAS.

Zanta-Boussif MA, Charrier S, Brice-Ouzet A, Martin S, Opolon P, Thrasher AJ, Hope TJ, Galy A. Zanta-Boussif MA, et al. Among authors: charrier s. Gene Ther. 2009 May;16(5):605-19. doi: 10.1038/gt.2009.3. Epub 2009 Mar 5. Gene Ther. 2009. PMID: 19262615

6

A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells.

Olivier A, Jeanson-Leh L, Bouma G, Compagno D, Blondeau J, Seye K, Charrier S, Burns S, Thrasher AJ, Danos O, Vainchenker W, Galy A. Olivier A, et al. Among authors: charrier s. Mol Ther. 2006 Apr;13(4):729-37. doi: 10.1016/j.ymthe.2005.11.003. Epub 2005 Dec 15. Mol Ther. 2006. PMID: 16360341 Free article.

7

Quantification of lentiviral vector copy numbers in individual hematopoietic colony-forming cells shows vector dose-dependent effects on the frequency and level of transduction.

Charrier S, Ferrand M, Zerbato M, Précigout G, Viornery A, Bucher-Laurent S, Benkhelifa-Ziyyat S, Merten OW, Perea J, Galy A. Charrier S, et al. Gene Ther. 2011 May;18(5):479-87. doi: 10.1038/gt.2010.163. Epub 2010 Dec 16. Gene Ther. 2011. PMID: 21160533 Free PMC article.

8

Diverse genomic integration of a lentiviral vector developed for the treatment of Wiskott-Aldrich syndrome.

Mantovani J, Charrier S, Eckenberg R, Saurin W, Danos O, Perea J, Galy A. Mantovani J, et al. Among authors: charrier s. J Gene Med. 2009 Aug;11(8):645-54. doi: 10.1002/jgm.1346. J Gene Med. 2009. PMID: 19455589

9

Large-scale manufacture and characterization of a lentiviral vector produced for clinical ex vivo gene therapy application.

Merten OW, Charrier S, Laroudie N, Fauchille S, Dugué C, Jenny C, Audit M, Zanta-Boussif MA, Chautard H, Radrizzani M, Vallanti G, Naldini L, Noguiez-Hellin P, Galy A. Merten OW, et al. Among authors: charrier s. Hum Gene Ther. 2011 Mar;22(3):343-56. doi: 10.1089/hum.2010.060. Epub 2011 Mar 7. Hum Gene Ther. 2011. PMID: 21043787

10

Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome.

Hacein-Bey Abina S, Gaspar HB, Blondeau J, Caccavelli L, Charrier S, Buckland K, Picard C, Six E, Himoudi N, Gilmour K, McNicol AM, Hara H, Xu-Bayford J, Rivat C, Touzot F, Mavilio F, Lim A, Treluyer JM, Héritier S, Lefrère F, Magalon J, Pengue-Koyi I, Honnet G, Blanche S, Sherman EA, Male F, Berry C, Malani N, Bushman FD, Fischer A, Thrasher AJ, Galy A, Cavazzana M. Hacein-Bey Abina S, et al. Among authors: charrier s. JAMA. 2015 Apr 21;313(15):1550-63. doi: 10.1001/jama.2015.3253. JAMA. 2015. PMID: 25898053 Free PMC article. Clinical Trial.

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