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Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.
de Lange MJ, Razzaq L, Versluis M, Verlinde S, Dogrusöz M, Böhringer S, Marinkovic M, Luyten GP, de Keizer RJ, de Gruijl FR, Jager MJ, van der Velden PA. de Lange MJ, et al. Among authors: dogrusoz m. PLoS One. 2015 Sep 14;10(9):e0138002. doi: 10.1371/journal.pone.0138002. eCollection 2015. PLoS One. 2015. PMID: 26368812 Free PMC article.
The genetic basis of uveal melanoma.
Nielsen M, Dogrusöz M, Bleeker JC, Kroes WG, van Asperen CA, Marinkovic M, Luyten GP, Jager MJ. Nielsen M, et al. Among authors: dogrusoz m. J Fr Ophtalmol. 2015 Jun;38(6):516-21. doi: 10.1016/j.jfo.2015.04.003. Epub 2015 May 11. J Fr Ophtalmol. 2015. PMID: 25976137
Radiation Treatment Affects Chromosome Testing in Uveal Melanoma.
Dogrusöz M, Kroes WG, van Duinen SG, Creutzberg CL, Versluis M, Bleeker JC, Marinkovic M, Luyten GP, Jager MJ. Dogrusöz M, et al. Invest Ophthalmol Vis Sci. 2015 Sep;56(10):5956-64. doi: 10.1167/iovs.15-17092. Invest Ophthalmol Vis Sci. 2015. PMID: 26393462
Uveal Melanoma Treatment and Prognostication.
Dogrusöz M, Jager MJ, Damato B. Dogrusöz M, et al. Asia Pac J Ophthalmol (Phila). 2017 Mar-Apr;6(2):186-196. doi: 10.22608/APO.201734. Asia Pac J Ophthalmol (Phila). 2017. PMID: 28399342 Free article. Review.
Genetic prognostication in uveal melanoma.
Dogrusöz M, Jager MJ. Dogrusöz M, et al. Acta Ophthalmol. 2018 Jun;96(4):331-347. doi: 10.1111/aos.13580. Epub 2017 Nov 4. Acta Ophthalmol. 2018. PMID: 29105334 Free article. Review.
In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations.
Piaggio F, Croce M, Reggiani F, Monti P, Bernardi C, Ambrosio M, Banelli B, Dogrusöz M, Jockers R, Bordo D, Puzone R, Viaggi S, Coviello D, Lanza FB, Bartolucci M, Petretto A, Mosci C, Gangemi R, van der Velden PA, Jager MJ, Pfeffer U, Amaro A. Piaggio F, et al. Among authors: dogrusoz m. Eur J Cancer. 2022 Jul;170:27-41. doi: 10.1016/j.ejca.2022.04.013. Epub 2022 May 14. Eur J Cancer. 2022. PMID: 35580369
Genetic evolution of uveal melanoma guides the development of an inflammatory microenvironment.
Gezgin G, Dogrusöz M, van Essen TH, Kroes WGM, Luyten GPM, van der Velden PA, Walter V, Verdijk RM, van Hall T, van der Burg SH, Jager MJ. Gezgin G, et al. Among authors: dogrusoz m. Cancer Immunol Immunother. 2017 Jul;66(7):903-912. doi: 10.1007/s00262-017-1991-1. Epub 2017 Apr 8. Cancer Immunol Immunother. 2017. PMID: 28391358 Free PMC article.
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