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Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization.
Asokan M, Rudicell RS, Louder M, McKee K, O'Dell S, Stewart-Jones G, Wang K, Xu L, Chen X, Choe M, Chuang G, Georgiev IS, Joyce MG, Kirys T, Ko S, Pegu A, Shi W, Todd JP, Yang Z, Bailer RT, Rao S, Kwong PD, Nabel GJ, Mascola JR. Asokan M, et al. J Virol. 2015 Dec;89(24):12501-12. doi: 10.1128/JVI.02097-15. Epub 2015 Oct 7. J Virol. 2015. PMID: 26446600 Free PMC article.
Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Cale EM, Gorman J, Radakovich NA, Crooks ET, Osawa K, Tong T, Li J, Nagarajan R, Ozorowski G, Ambrozak DR, Asokan M, Bailer RT, Bennici AK, Chen X, Doria-Rose NA, Druz A, Feng Y, Joyce MG, Louder MK, O'Dell S, Oliver C, Pancera M, Connors M, Hope TJ, Kepler TB, Wyatt RT, Ward AB, Georgiev IS, Kwong PD, Mascola JR, Binley JM. Cale EM, et al. Among authors: asokan m. Immunity. 2017 May 16;46(5):777-791.e10. doi: 10.1016/j.immuni.2017.04.011. Immunity. 2017. PMID: 28514685 Free PMC article.
Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.
Wibmer CK, Gorman J, Ozorowski G, Bhiman JN, Sheward DJ, Elliott DH, Rouelle J, Smira A, Joyce MG, Ndabambi N, Druz A, Asokan M, Burton DR, Connors M, Abdool Karim SS, Mascola JR, Robinson JE, Ward AB, Williamson C, Kwong PD, Morris L, Moore PL. Wibmer CK, et al. Among authors: asokan m. PLoS Pathog. 2017 Jan 11;13(1):e1006074. doi: 10.1371/journal.ppat.1006074. eCollection 2017 Jan. PLoS Pathog. 2017. PMID: 28076415 Free PMC article.
Immunogenicity of SARS-CoV-2 vaccines BBV152 (COVAXIN®) and ChAdOx1 nCoV-19 (COVISHIELD™) in seronegative and seropositive individuals in India: a multicentre, nonrandomised observational study.
Asokan MS, Joan RF, Babji S, Dayma G, Nadukkandy P, Subrahmanyam V, Pandey A, Malagi G, Arya P, Mahajan V, Bhavikatti J, Pawar K, Thorat A, Shah P, Goud RB, Roy B, Rajukutty S, Immanuel S, Agarwal D, Saha S, Shivaraj A, Panikulam P, Shome R, Gulzar SE, Sharma AU, Naik A, Talashi S, Belekar M, Yadav R, Khude P, V M, Shivalingaiah S, Deshmukh U, Bhise C, Joshi M, Inbaraj LR, Chandrasingh S, Ghose A, Jamora C, Karumbati AS, Sundaramurthy V, Johnson A, Ramesh N, Chetan N, Parthiban C, Ahmed A, Rakshit S, Adiga V, D'souza G, Rale V, George CE, John J, Kawade A, Chaturvedi A, Raghunathan A, Dias M, Bhosale A, Raghu P, Shashidhara LS, Vyakarnam A, Bal V, Kang G, Mayor S. Asokan MS, et al. Lancet Reg Health Southeast Asia. 2024 Feb 27;22:100361. doi: 10.1016/j.lansea.2024.100361. eCollection 2024 Mar. Lancet Reg Health Southeast Asia. 2024. PMID: 38482152 Free PMC article.
Polyfunctional CD4 T-cells correlating with neutralising antibody is a hallmark of COVISHIELDTM and COVAXIN® induced immunity in COVID-19 exposed Indians.
Rakshit S, Babji S, Parthiban C, Madhavan R, Adiga V, J SE, Chetan Kumar N, Ahmed A, Shivalingaiah S, Shashikumar N, V M, Johnson AR, Ramesh N, B RG, Asokan M, Mayor S, Kang G, D'souza G, Dias M, Vyakarnam A. Rakshit S, et al. Among authors: asokan m. NPJ Vaccines. 2023 Sep 14;8(1):134. doi: 10.1038/s41541-023-00731-w. NPJ Vaccines. 2023. PMID: 37709772 Free PMC article.
Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain.
Kwon YD, Pegu A, Yang ES, Zhang B, Bender MF, Asokan M, Liu Q, McKee K, Lin BC, Liu T, Louder MK, Rawi R, Reveiz M, Schaub AJ, Shen CH, Doria-Rose NA, Lusso P, Mascola JR, Kwong PD. Kwon YD, et al. Among authors: asokan m. MAbs. 2023 Jan-Dec;15(1):2223350. doi: 10.1080/19420862.2023.2223350. MAbs. 2023. PMID: 37345226 Free PMC article.
New revelations from the zone of uncertainty.
Asokan MM, Polley DB. Asokan MM, et al. Neuron. 2023 Mar 1;111(5):601-603. doi: 10.1016/j.neuron.2023.01.028. Neuron. 2023. PMID: 36863318 Free article.
41 results