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PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.
Zhang Y, Mao D, Roswit WT, Jin X, Patel AC, Patel DA, Agapov E, Wang Z, Tidwell RM, Atkinson JJ, Huang G, McCarthy R, Yu J, Yun NE, Paessler S, Lawson TG, Omattage NS, Brett TJ, Holtzman MJ. Zhang Y, et al. Among authors: brett tj. Nat Immunol. 2015 Dec;16(12):1215-27. doi: 10.1038/ni.3279. Epub 2015 Oct 19. Nat Immunol. 2015. PMID: 26479788 Free PMC article.
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
Alevy YG, Patel AC, Romero AG, Patel DA, Tucker J, Roswit WT, Miller CA, Heier RF, Byers DE, Brett TJ, Holtzman MJ. Alevy YG, et al. Among authors: brett tj. J Clin Invest. 2012 Dec;122(12):4555-68. doi: 10.1172/JCI64896. Epub 2012 Nov 26. J Clin Invest. 2012. PMID: 23187130 Free PMC article.
The role of CLCA proteins in inflammatory airway disease.
Patel AC, Brett TJ, Holtzman MJ. Patel AC, et al. Among authors: brett tj. Annu Rev Physiol. 2009;71:425-49. doi: 10.1146/annurev.physiol.010908.163253. Annu Rev Physiol. 2009. PMID: 18954282 Free PMC article. Review.
Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.
Yurtsever Z, Sala-Rabanal M, Randolph DT, Scheaffer SM, Roswit WT, Alevy YG, Patel AC, Heier RF, Romero AG, Nichols CG, Holtzman MJ, Brett TJ. Yurtsever Z, et al. Among authors: brett tj. J Biol Chem. 2012 Dec 7;287(50):42138-49. doi: 10.1074/jbc.M112.410282. Epub 2012 Oct 30. J Biol Chem. 2012. PMID: 23112050 Free PMC article.
43 results