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PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.
Nat Immunol. 2015 Dec;16(12):1215-27. doi: 10.1038/ni.3279. Epub 2015 Oct 19.
Nat Immunol. 2015.
PMID: 26479788
Free PMC article.
IL-12 p80-dependent macrophage recruitment primes the host for increased survival following a lethal respiratory viral infection.
Gunsten S, Mikols CL, Grayson MH, Schwendener RA, Agapov E, Tidwell RM, Cannon CL, Brody SL, Walter MJ.
Gunsten S, et al. Among authors: tidwell rm.
Immunology. 2009 Apr;126(4):500-13. doi: 10.1111/j.1365-2567.2008.02923.x. Epub 2008 Sep 6.
Immunology. 2009.
PMID: 18783467
Free PMC article.
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Stat1 depends on transcriptional synergy with Sp1.
Look DC, Pelletier MR, Tidwell RM, Roswit WT, Holtzman MJ.
Look DC, et al. Among authors: tidwell rm.
J Biol Chem. 1995 Dec 22;270(51):30264-7. doi: 10.1074/jbc.270.51.30264.
J Biol Chem. 1995.
PMID: 8530443
Free article.
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Targeted inhibition of interferon-gamma-dependent intercellular adhesion molecule-1 (ICAM-1) expression using dominant-negative Stat1.
Walter MJ, Look DC, Tidwell RM, Roswit WT, Holtzman MJ.
Walter MJ, et al. Among authors: tidwell rm.
J Biol Chem. 1997 Nov 7;272(45):28582-9. doi: 10.1074/jbc.272.45.28582.
J Biol Chem. 1997.
PMID: 9353323
Free article.
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Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease.
Kim EY, Battaile JT, Patel AC, You Y, Agapov E, Grayson MH, Benoit LA, Byers DE, Alevy Y, Tucker J, Swanson S, Tidwell R, Tyner JW, Morton JD, Castro M, Polineni D, Patterson GA, Schwendener RA, Allard JD, Peltz G, Holtzman MJ.
Kim EY, et al.
Nat Med. 2008 Jun;14(6):633-40. doi: 10.1038/nm1770. Epub 2008 May 18.
Nat Med. 2008.
PMID: 18488036
Free PMC article.
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BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes.
Ehlers A, Xie W, Agapov E, Brown S, Steinberg D, Tidwell R, Sajol G, Schutz R, Weaver R, Yu H, Castro M, Bacharier LB, Wang X, Holtzman MJ, Haspel JA.
Ehlers A, et al.
Mucosal Immunol. 2018 Jan;11(1):97-111. doi: 10.1038/mi.2017.24. Epub 2017 Apr 12.
Mucosal Immunol. 2018.
PMID: 28401936
Free PMC article.
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Macrophage chitinase 1 stratifies chronic obstructive lung disease.
Agapov E, Battaile JT, Tidwell R, Hachem R, Patterson GA, Pierce RA, Atkinson JJ, Holtzman MJ.
Agapov E, et al.
Am J Respir Cell Mol Biol. 2009 Oct;41(4):379-84. doi: 10.1165/rcmb.2009-0122rc. Epub 2009 Jun 2.
Am J Respir Cell Mol Biol. 2009.
PMID: 19491341
Free PMC article.
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Virus-inducible expression of a host chemokine gene relies on replication-linked mRNA stabilization.
Koga T, Sardiña E, Tidwell RM, Pelletier M, Look DC, Holtzman MJ.
Koga T, et al. Among authors: tidwell rm.
Proc Natl Acad Sci U S A. 1999 May 11;96(10):5680-5. doi: 10.1073/pnas.96.10.5680.
Proc Natl Acad Sci U S A. 1999.
PMID: 10318944
Free PMC article.
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