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A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence.
Menachery VD, Yount BL Jr, Debbink K, Agnihothram S, Gralinski LE, Plante JA, Graham RL, Scobey T, Ge XY, Donaldson EF, Randell SH, Lanzavecchia A, Marasco WA, Shi ZL, Baric RS. Menachery VD, et al. Among authors: gralinski le. Nat Med. 2015 Dec;21(12):1508-13. doi: 10.1038/nm.3985. Epub 2015 Nov 9. Nat Med. 2015. PMID: 26552008 Free PMC article.
Genetic analysis of complex traits in the emerging Collaborative Cross.
Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, de Villena FP, Churchill GA. Aylor DL, et al. Among authors: gralinski le. Genome Res. 2011 Aug;21(8):1213-22. doi: 10.1101/gr.111310.110. Epub 2011 Mar 15. Genome Res. 2011. PMID: 21406540 Free PMC article.
A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge.
Bolles M, Deming D, Long K, Agnihothram S, Whitmore A, Ferris M, Funkhouser W, Gralinski L, Totura A, Heise M, Baric RS. Bolles M, et al. J Virol. 2011 Dec;85(23):12201-15. doi: 10.1128/JVI.06048-11. Epub 2011 Sep 21. J Virol. 2011. PMID: 21937658 Free PMC article.
Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection.
Peng X, Gralinski L, Ferris MT, Frieman MB, Thomas MJ, Proll S, Korth MJ, Tisoncik JR, Heise M, Luo S, Schroth GP, Tumpey TM, Li C, Kawaoka Y, Baric RS, Katze MG. Peng X, et al. mBio. 2011 Nov 15;2(6):e00198-11. doi: 10.1128/mBio.00198-11. Print 2011. mBio. 2011. PMID: 22086488 Free PMC article.
Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells.
Sims AC, Tilton SC, Menachery VD, Gralinski LE, Schäfer A, Matzke MM, Webb-Robertson BJ, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR 3rd, Burkett SE, Zornetzer G, Tseng CT, Metz TO, Pickles R, McWeeney S, Smith RD, Katze MG, Waters KM, Baric RS. Sims AC, et al. Among authors: gralinski le. J Virol. 2013 Apr;87(7):3885-902. doi: 10.1128/JVI.02520-12. Epub 2013 Jan 30. J Virol. 2013. PMID: 23365422 Free PMC article.
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.
Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, Wang J, Churchill GA, Threadgill DW, McWeeney SK, Katze MG, Pardo-Manuel de Villena F, Baric RS, Heise MT. Ferris MT, et al. Among authors: gralinski le. PLoS Pathog. 2013 Feb;9(2):e1003196. doi: 10.1371/journal.ppat.1003196. Epub 2013 Feb 28. PLoS Pathog. 2013. PMID: 23468633 Free PMC article.
Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice.
Tchitchek N, Eisfeld AJ, Tisoncik-Go J, Josset L, Gralinski LE, Bécavin C, Tilton SC, Webb-Robertson BJ, Ferris MT, Totura AL, Li C, Neumann G, Metz TO, Smith RD, Waters KM, Baric R, Kawaoka Y, Katze MG. Tchitchek N, et al. Among authors: gralinski le. BMC Syst Biol. 2013 Jul 29;7:69. doi: 10.1186/1752-0509-7-69. BMC Syst Biol. 2013. PMID: 23895213 Free PMC article.
86 results