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Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study.
Jack CR Jr, Therneau TM, Wiste HJ, Weigand SD, Knopman DS, Lowe VJ, Mielke MM, Vemuri P, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC. Jack CR Jr, et al. Among authors: therneau tm. Lancet Neurol. 2016 Jan;15(1):56-64. doi: 10.1016/S1474-4422(15)00323-3. Epub 2015 Nov 18. Lancet Neurol. 2016. PMID: 26597325 Free PMC article.
Age-specific and sex-specific prevalence of cerebral β-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50-95 years: a cross-sectional study.
Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Knopman DS, Lowe V, Vemuri P, Mielke MM, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC. Jack CR Jr, et al. Among authors: therneau tm. Lancet Neurol. 2017 Jun;16(6):435-444. doi: 10.1016/S1474-4422(17)30077-7. Epub 2017 Apr 26. Lancet Neurol. 2017. PMID: 28456479 Free PMC article.
Widespread brain tau and its association with ageing, Braak stage and Alzheimer's dementia.
Lowe VJ, Wiste HJ, Senjem ML, Weigand SD, Therneau TM, Boeve BF, Josephs KA, Fang P, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, Graff-Radford J, Schwarz CG, Machulda MM, Mielke MM, Roberts RO, Knopman DS, Petersen RC, Jack CR Jr. Lowe VJ, et al. Among authors: therneau tm. Brain. 2018 Jan 1;141(1):271-287. doi: 10.1093/brain/awx320. Brain. 2018. PMID: 29228201 Free PMC article. Clinical Trial.
Joint associations of β-amyloidosis and cortical thickness with cognition.
Knopman DS, Lundt ES, Therneau TM, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC, Jack CR Jr. Knopman DS, et al. Among authors: therneau tm. Neurobiol Aging. 2018 May;65:121-131. doi: 10.1016/j.neurobiolaging.2018.01.017. Epub 2018 Feb 2. Neurobiol Aging. 2018. PMID: 29471214 Free PMC article.
Longitudinal tau PET in ageing and Alzheimer's disease.
Jack CR Jr, Wiste HJ, Schwarz CG, Lowe VJ, Senjem ML, Vemuri P, Weigand SD, Therneau TM, Knopman DS, Gunter JL, Jones DT, Graff-Radford J, Kantarci K, Roberts RO, Mielke MM, Machulda MM, Petersen RC. Jack CR Jr, et al. Among authors: therneau tm. Brain. 2018 May 1;141(5):1517-1528. doi: 10.1093/brain/awy059. Brain. 2018. PMID: 29538647 Free PMC article.
Predicting Progression to Mild Cognitive Impairment.
Petersen RC, Lundt ES, Therneau TM, Weigand SD, Knopman DS, Mielke MM, Roberts RO, Lowe VJ, Machulda MM, Kremers WK, Geda YE, Jack CR Jr. Petersen RC, et al. Among authors: therneau tm. Ann Neurol. 2019 Jan;85(1):155-160. doi: 10.1002/ana.25388. Epub 2019 Jan 7. Ann Neurol. 2019. PMID: 30521086 Free PMC article.
Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults.
Lowe VJ, Bruinsma TJ, Wiste HJ, Min HK, Weigand SD, Fang P, Senjem ML, Therneau TM, Boeve BF, Josephs KA, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, Graff-Radford J, Schwarz CG, Machulda MM, Mielke MM, Roberts RO, Knopman DS, Petersen RC, Jack CR Jr. Lowe VJ, et al. Among authors: therneau tm. Neurology. 2019 Jul 2;93(1):e29-e39. doi: 10.1212/WNL.0000000000007728. Epub 2019 May 30. Neurology. 2019. PMID: 31147421 Free PMC article.
Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia.
Jack CR Jr, Wiste HJ, Therneau TM, Weigand SD, Knopman DS, Mielke MM, Lowe VJ, Vemuri P, Machulda MM, Schwarz CG, Gunter JL, Senjem ML, Graff-Radford J, Jones DT, Roberts RO, Rocca WA, Petersen RC. Jack CR Jr, et al. Among authors: therneau tm. JAMA. 2019 Jun 18;321(23):2316-2325. doi: 10.1001/jama.2019.7437. JAMA. 2019. PMID: 31211344 Free PMC article.
Prevalence of Biologically vs Clinically Defined Alzheimer Spectrum Entities Using the National Institute on Aging-Alzheimer's Association Research Framework.
Jack CR Jr, Therneau TM, Weigand SD, Wiste HJ, Knopman DS, Vemuri P, Lowe VJ, Mielke MM, Roberts RO, Machulda MM, Graff-Radford J, Jones DT, Schwarz CG, Gunter JL, Senjem ML, Rocca WA, Petersen RC. Jack CR Jr, et al. Among authors: therneau tm. JAMA Neurol. 2019 Oct 1;76(10):1174-1183. doi: 10.1001/jamaneurol.2019.1971. JAMA Neurol. 2019. PMID: 31305929 Free PMC article.
394 results