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∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.
Pankow S, Bamberger C, Calzolari D, Martínez-Bartolomé S, Lavallée-Adam M, Balch WE, Yates JR 3rd. Pankow S, et al. Among authors: balch we. Nature. 2015 Dec 24;528(7583):510-6. doi: 10.1038/nature15729. Epub 2015 Nov 30. Nature. 2015. PMID: 26618866 Free PMC article.
Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway.
Yoo JS, Moyer BD, Bannykh S, Yoo HM, Riordan JR, Balch WE. Yoo JS, et al. Among authors: balch we. J Biol Chem. 2002 Mar 29;277(13):11401-9. doi: 10.1074/jbc.M110263200. Epub 2002 Jan 17. J Biol Chem. 2002. PMID: 11799116 Free article.
., Bannykh, G. I., Fish, K. N., Moyer, B. D., Riordan, J. R., and Balch, W. E. (2000) Traffic 1, 852-870), raising the possibility of a novel trafficking pathway through the early secretory pathway. We now report that export of CFTR from the ER is regulated by the c …
., Bannykh, G. I., Fish, K. N., Moyer, B. D., Riordan, J. R., and Balch, W. E. (2000) Traffic 1, 852-870), raising the possibility of …
Metalloendoprotease cleavage triggers gelsolin amyloidogenesis.
Page LJ, Suk JY, Huff ME, Lim HJ, Venable J, Yates J, Kelly JW, Balch WE. Page LJ, et al. Among authors: balch we. EMBO J. 2005 Dec 7;24(23):4124-32. doi: 10.1038/sj.emboj.7600872. Epub 2005 Nov 10. EMBO J. 2005. PMID: 16281052 Free PMC article.
Structure of the Sec13/31 COPII coat cage.
Stagg SM, Gürkan C, Fowler DM, LaPointe P, Foss TR, Potter CS, Carragher B, Balch WE. Stagg SM, et al. Among authors: balch we. Nature. 2006 Jan 12;439(7073):234-8. doi: 10.1038/nature04339. Nature. 2006. PMID: 16407955
Chemical and biological folding contribute to temperature-sensitive DeltaF508 CFTR trafficking.
Wang X, Koulov AV, Kellner WA, Riordan JR, Balch WE. Wang X, et al. Among authors: balch we. Traffic. 2008 Nov;9(11):1878-93. doi: 10.1111/j.1600-0854.2008.00806.x. Epub 2008 Jul 30. Traffic. 2008. PMID: 18764821 Free PMC article.
Proteostasis (Balch WE, Morimoto RI, Dillin A, Kelly JW. Adapting proteostasis for disease intervention. ...We find that DeltaF508 export requires a local biological folding environment that is sensitive to heat/stress-inducible factors found in some cell typ …
Proteostasis (Balch WE, Morimoto RI, Dillin A, Kelly JW. Adapting proteostasis for disease intervention. ...We find tha …
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.
Hutt DM, Herman D, Rodrigues AP, Noel S, Pilewski JM, Matteson J, Hoch B, Kellner W, Kelly JW, Schmidt A, Thomas PJ, Matsumura Y, Skach WR, Gentzsch M, Riordan JR, Sorscher EJ, Okiyoneda T, Yates JR 3rd, Lukacs GL, Frizzell RA, Manning G, Gottesfeld JM, Balch WE. Hutt DM, et al. Among authors: balch we. Nat Chem Biol. 2010 Jan;6(1):25-33. doi: 10.1038/nchembio.275. Epub 2009 Dec 6. Nat Chem Biol. 2010. PMID: 19966789 Free PMC article.
244 results