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A randomized, double-blind, Phase 2 study to evaluate subjective and objective outcomes in patients with acute bacterial skin and skin structure infections treated with delafloxacin, linezolid or vancomycin.
Kingsley J, Mehra P, Lawrence LE, Henry E, Duffy E, Cammarata SK, Pullman J. Kingsley J, et al. Among authors: duffy e. J Antimicrob Chemother. 2016 Mar;71(3):821-9. doi: 10.1093/jac/dkv411. Epub 2015 Dec 17. J Antimicrob Chemother. 2016. PMID: 26679243 Free PMC article. Clinical Trial.
Activity of RX-P873, a novel pyrrolocytosine, against Gram-negative bacteria.
Morrissey I, Magnet S, Genet E, Jeandey P, Marra A, Hawser S, Duffy E. Morrissey I, et al. Among authors: duffy e. Int J Antimicrob Agents. 2015 Sep;46(3):352-4. doi: 10.1016/j.ijantimicag.2015.06.001. Epub 2015 Jun 19. Int J Antimicrob Agents. 2015. PMID: 26159867 No abstract available.
Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
Zhou J, Bhattacharjee A, Chen S, Chen Y, Duffy E, Farmer J, Goldberg J, Hanselmann R, Ippolito JA, Lou R, Orbin A, Oyelere A, Salvino J, Springer D, Tran J, Wang D, Wu Y, Johnson G. Zhou J, et al. Among authors: duffy e. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6175-8. doi: 10.1016/j.bmcl.2008.10.011. Epub 2008 Oct 7. Bioorg Med Chem Lett. 2008. PMID: 18947996
Design at the atomic level: generation of novel hybrid biaryloxazolidinones as promising new antibiotics.
Zhou J, Bhattacharjee A, Chen S, Chen Y, Duffy E, Farmer J, Goldberg J, Hanselmann R, Ippolito JA, Lou R, Orbin A, Oyelere A, Salvino J, Springer D, Tran J, Wang D, Wu Y, Johnson G. Zhou J, et al. Among authors: duffy e. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6179-83. doi: 10.1016/j.bmcl.2008.10.014. Epub 2008 Oct 7. Bioorg Med Chem Lett. 2008. PMID: 18951792
Structure-based drug design meets the ribosome.
Franceschi F, Duffy EM. Franceschi F, et al. Biochem Pharmacol. 2006 Mar 30;71(7):1016-25. doi: 10.1016/j.bcp.2005.12.026. Epub 2006 Jan 26. Biochem Pharmacol. 2006. PMID: 16443192 Review.
464 results