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Page 1
Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.
York AG, Williams KJ, Argus JP, Zhou QD, Brar G, Vergnes L, Gray EE, Zhen A, Wu NC, Yamada DH, Cunningham CR, Tarling EJ, Wilks MQ, Casero D, Gray DH, Yu AK, Wang ES, Brooks DG, Sun R, Kitchen SG, Wu TT, Reue K, Stetson DB, Bensinger SJ. York AG, et al. Among authors: argus jp. Cell. 2015 Dec 17;163(7):1716-29. doi: 10.1016/j.cell.2015.11.045. Epub 2015 Dec 10. Cell. 2015. PMID: 26686653 Free PMC article.
Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity.
Kidani Y, Elsaesser H, Hock MB, Vergnes L, Williams KJ, Argus JP, Marbois BN, Komisopoulou E, Wilson EB, Osborne TF, Graeber TG, Reue K, Brooks DG, Bensinger SJ. Kidani Y, et al. Among authors: argus jp. Nat Immunol. 2013 May;14(5):489-99. doi: 10.1038/ni.2570. Epub 2013 Apr 7. Nat Immunol. 2013. PMID: 23563690 Free PMC article.
An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity.
Williams KJ, Argus JP, Zhu Y, Wilks MQ, Marbois BN, York AG, Kidani Y, Pourzia AL, Akhavan D, Lisiero DN, Komisopoulou E, Henkin AH, Soto H, Chamberlain BT, Vergnes L, Jung ME, Torres JZ, Liau LM, Christofk HR, Prins RM, Mischel PS, Reue K, Graeber TG, Bensinger SJ. Williams KJ, et al. Among authors: argus jp. Cancer Res. 2013 May 1;73(9):2850-62. doi: 10.1158/0008-5472.CAN-13-0382-T. Epub 2013 Feb 25. Cancer Res. 2013. PMID: 23440422 Free PMC article.
Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis.
Mercer JL, Argus JP, Crabtree DM, Keenan MM, Wilks MQ, Chi JT, Bensinger SJ, Lavau CP, Wechsler DS. Mercer JL, et al. Among authors: argus jp. PLoS One. 2015 Jun 15;10(6):e0129776. doi: 10.1371/journal.pone.0129776. eCollection 2015. PLoS One. 2015. PMID: 26075887 Free PMC article.
In Vitro Biotransformation of the Nrf2 Activator Bardoxolone: Formation of an Epoxide Metabolite That Undergoes Two Novel Glutathione-Mediated Metabolic Pathways: Epoxide Reduction and Oxidative Elimination of Nitrile Moiety.
Kamel AM, Bowlin S, Anwar B, Reichard H, Argus J, Blair IA. Kamel AM, et al. Chem Res Toxicol. 2019 Nov 18;32(11):2268-2280. doi: 10.1021/acs.chemrestox.9b00289. Epub 2019 Oct 25. Chem Res Toxicol. 2019. PMID: 31613099 Free PMC article.