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Pediatric COVID-19 patients in South Brazil show abundant viral mRNA and strong specific anti-viral responses.
Fazolo T, Lima K, Fontoura JC, de Souza PO, Hilario G, Zorzetto R, Júnior LR, Pscheidt VM, de Castilhos Ferreira Neto J, Haubert AF, Gambin I, Oliveira AC, Mello RS, de Bastos Balbe E Gutierres M, Gassen RB, Coimbra LD, Borin A, Marques RE, Sartor ITS, Zavaglia GO, Fernandes IR, Nakaya HI, Varela FH, Polese-Bonatto M, Borges TJ, Callegari-Jacques SM, da Costa MSC, de Araujo Schwartz J, Scotta MC, Stein RT, Bonorino C. Fazolo T, et al. Among authors: gassen rb. Nat Commun. 2021 Nov 25;12(1):6844. doi: 10.1038/s41467-021-27120-y. Nat Commun. 2021. PMID: 34824230 Free PMC article.
RvD1 treatment during primary infection modulates memory response increasing viral load during respiratory viral reinfection.
de Freitas DDN, Marinho Franceschina C, Muller D, Hilario GT, Gassen RB, Fazolo T, de Lima Kaminski V, Bogo Chies JA, Maito F, Antunes KH, Zanin RF, Rodrigues LC Jr, Duarte de Souza AP. de Freitas DDN, et al. Among authors: gassen rb. Immunobiology. 2021 Nov;226(6):152151. doi: 10.1016/j.imbio.2021.152151. Epub 2021 Oct 31. Immunobiology. 2021. PMID: 34742024
CPBMF65, a synthetic human uridine phosphorylase-1 inhibitor, reduces HepG2 cell proliferation through cell cycle arrest and senescence.
da Silva EFG, Lima KG, Krause GC, Haute GV, Pedrazza L, Catarina AV, Gassen RB, de Souza Basso B, Dias HB, Luft C, Garcia MCR, Costa BP, Antunes GL, Basso LA, Donadio MVF, Machado P, de Oliveira JR. da Silva EFG, et al. Among authors: gassen rb. Invest New Drugs. 2020 Dec;38(6):1653-1663. doi: 10.1007/s10637-020-00941-2. Epub 2020 May 4. Invest New Drugs. 2020. PMID: 32367200
24 results