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Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs.
Kaczmarek JC, Patel AK, Kauffman KJ, Fenton OS, Webber MJ, Heartlein MW, DeRosa F, Anderson DG. Kaczmarek JC, et al. Among authors: heartlein mw. Angew Chem Int Ed Engl. 2016 Oct 24;55(44):13808-13812. doi: 10.1002/anie.201608450. Epub 2016 Sep 30. Angew Chem Int Ed Engl. 2016. PMID: 27690187 Free PMC article.
mRNA Delivery for Therapeutic Anti-HER2 Antibody Expression In Vivo.
Rybakova Y, Kowalski PS, Huang Y, Gonzalez JT, Heartlein MW, DeRosa F, Delcassian D, Anderson DG. Rybakova Y, et al. Among authors: heartlein mw. Mol Ther. 2019 Aug 7;27(8):1415-1423. doi: 10.1016/j.ymthe.2019.05.012. Epub 2019 May 18. Mol Ther. 2019. PMID: 31160223 Free PMC article.
Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo.
Kauffman KJ, Mir FF, Jhunjhunwala S, Kaczmarek JC, Hurtado JE, Yang JH, Webber MJ, Kowalski PS, Heartlein MW, DeRosa F, Anderson DG. Kauffman KJ, et al. Among authors: heartlein mw. Biomaterials. 2016 Dec;109:78-87. doi: 10.1016/j.biomaterials.2016.09.006. Epub 2016 Sep 25. Biomaterials. 2016. PMID: 27680591 Free PMC article.
Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes.
Fenton OS, Kauffman KJ, Kaczmarek JC, McClellan RL, Jhunjhunwala S, Tibbitt MW, Zeng MD, Appel EA, Dorkin JR, Mir FF, Yang JH, Oberli MA, Heartlein MW, DeRosa F, Langer R, Anderson DG. Fenton OS, et al. Among authors: heartlein mw. Adv Mater. 2017 Sep;29(33). doi: 10.1002/adma.201606944. Epub 2017 Jul 6. Adv Mater. 2017. PMID: 28681930
37 results